Results 321 to 330 of about 381,964 (386)

Resting-state memory consolidation in Attention-Deficit/Hyperactivity Disorder. [PDF]

PLoS One
Scalia B, Wamsley EJ.
europepmc   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Increasing incidence of ADHD among children, adolescents and young adults: COVID-19 pandemic-driven trend in Korea (2012-2023). [PDF]

BMJ Ment Health
Song J, Park SJ, Jeong S, Chun AY, Park SM.   +4 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

ADHD and schizophrenia: Mere prodromal variant or homogeneous subgroup? [PDF]

Schizophr Res Cogn
Schulze JB, Simnacher F, Müller TJ, Kirchebner J, Quatela F, Mikutta C, Euler S, von Känel R, Günther MP.   +8 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Increased Prescribing of Attention-Deficit/Hyperactivity Disorder Medication and Real-World Outcomes Over Time.

JAMA Psychiatry
Li L, Coghill D, Sjölander A, Yao H, Zhang L, Kuja-Halkola R, Brikell I, Lichtenstein P, D'Onofrio BM, Larsson H, Chang Z.   +10 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Adult ADHD and comorbid anxiety and depressive disorders: a review of etiology and treatment. [PDF]

Front Psychiatry
Fu X, Wu W, Wu Y, Liu X, Liang W, Wu R, Li Y.   +6 more
europepmc   +1 more source

Common and rare variant analyses implicate late-infancy cerebellar development and immune genes in ADHD. [PDF]

J Neurodev Disord
Zhong Y, Baum LW, Tubbs JD, Ye R, Chen LH, Wu T, Hung SF, Tang CP, Ho TP, Moyzis R, Swanson J, Lee CC, Sham PC, Leung PWL.   +13 more
europepmc   +1 more source