Results 101 to 110 of about 1,176,873 (245)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

HABIT BASED CONSUMPTIONS IN THE MEDITERRANEAN DIET AND THE RELATIONSHIP WITH ANTHROPOMETRIC PARAMETERS IN YOUNG FEMALE KAYAKERS [PDF]

open access: yes, 2014
Introducción: Los hábitos alimentarios y la composición corporal son posiblemente dos de los aspectos modificables que más pueden influir en el rendimiento deportivo, principalmente en los deportes individuales.
Alacid, Fernando   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Diagnóstico y tratamiento de las fracturas dentarias asociadas a la parafunción (parte 2) Diagnosis and management of fractured teeth associated with parafunction (part 2)

open access: yesRevista de la Asociación Odontológica Argentina, 2014
Resumen Objetivo: Presentar la resolución clínica de una fractura dentaria incompleta mediante la realización de una restauración adherida de tipo onlay.
Carlos Adrián Fernández   +3 more
doaj  

La europeización de España (1986-2006) [PDF]

open access: yes, 2007
Este artículo ofrece un balance de las transformaciones experimentadas por España desde su adhesión a la Comunidad Europea y plantea los principales retos futuros a los que se enfrenta España, tanto internos como en el ámbito exterior.
Piedrafita, Sonia   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

FUERZAS DE SUPERFICIE Y ADHESIÓN EN SISTEMAS CELULÓSICOS: NUEVA FORMA DE EVALUAR FIJACIÓN/DISPERSIÓN DE RESINA EN LA FABRICACIÓN DE PAPEL/CELULOSA SURFACE FORCES AND ADHESION IN CELLULOSE SYSTEMS: NEW WAY TO EVALUATE RESIN FIXATION/DISPERSION IN THE MANUFACTURE OF PAPER/CELLULOSE

open access: yesMaderas: Ciencia y Tecnología, 2010
Las fuerzas superficiales entre partículas coloidales de resina y fibra dominan el comportamiento y las propiedades finales de papel y celulosa. Aquí se describe el uso de Microscopía de Fuerza Atómica (AFM) para medir directamente las fuerzas de ...
Sergio M Acuña, Pedro G Toledo
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Recomendación de la Comisión sobre el progreso de Turquía hacia la adhesión: reacciones desde Turquía [PDF]

open access: yes, 2004
La recomendación de la Comisión para la apertura de negociaciones en Turquía ha originado un álgido debate acerca de las condiciones y consecuencias del proceso de negociación entre Ankara y Bruselas.
Rodríguez López, Carmen
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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