Results 61 to 70 of about 960,956 (198)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
El Referéndum sobre la permanencia de España en la OTAN
Revista UNISCI, 2011 En el presente artículo se hace una revisión histórica y cronológica del proceso de adhesión de España a la OTAN, proceso iniciado durante el primer Gobierno de la Unión de Centro Democrático (UCD) de Adolfo Suárez y que culminó con el referéndum ...
Juan Antonio Martínez Sánchez
doaj
Ehquidad, 2019 A menudo la administración pública de los servicios de salud implementa estrategias para acercarse a las necesidades de los usuarios mediante la promoción de estilos de vida evocativos de accidentes y enfermedades, pero estas sólo son parte de un ...
Sofía López de Nava-Tapia +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Revista Derecho y SaludEl presente trabajo tiene como objetivo presentar un análisis comparativo de la legislación nacional y la ley de la provincia de Santa Fe que regulan el reconocimiento, acceso y cobertura de los cuidados paliativos con la finalidad de detectar puntos en
Elisabet Agustina Vidal
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Adesão de pacientes hipertensos ao tratamento medicamentoso
Revista Brasileira de Enfermagem, 2014 Estudo descritivo, de corte transversal, realizado em um Centro de Hipertensão e Metabologia, cujo objetivo foi identificar a adesão à terapêutica medicamentosa em pacientes hipertensos, bem como identificar os fatores, diretamente relacionados ao ...
Amanda Silva de Macêdo Bezerra +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source