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MAAP: Malarial adhesins and adhesin‐like proteins predictor

Proteins: Structure, Function, and Bioinformatics, 2008
AbstractMalaria caused by protozoan parasites belonging to the genus Plasmodium is a dreaded disease, second only to tuberculosis. The emergence of parasites resistant to commonly used drugs and the lack of availability of vaccines aggravates the problem. One of the preventive approaches targets adhesion of parasites to host cells and tissues. Adhesion
Faraz Alam, Ansari   +4 more
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Collagen adhesin–nanoparticle interaction impairs adhesin's ligand binding mechanism

Biochimica et Biophysica Acta (BBA) - General Subjects, 2012
Pathogenic bacteria specifically recognize extracellular matrix (ECM) molecules of the host (e.g. collagen, fibrinogen and fibronectin) through their surface proteins known as MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules) and initiate colonization.
Aribam Swarmistha, Devi   +4 more
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Clostridium difficile Adhesins

2016
Clostridium difficile is responsible for a large spectrum of intestinal diseases ranging from mild diarrhea to fatal colitis depending on the one hand on the strain virulence and on the other on the host. The pathogenesis of C. difficile infection could be seen as a three-step process that takes place after disruption of the digestive microbiota by ...
Séverine, Péchiné   +2 more
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Adhesins of Escherichia coli

Acta Biotechnologica, 1990
AbstractE. coli has got increasing importance as a causative agent of intestinal and extra‐intestinal diseases. In both these infections adhesion of the bacteria to mucous surface cells are initial events for coionization and development of infection. Adhesins are bacterial recognition proteins which specifically interact with carbohydrate moieties of ...
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Adhesins in Candida albicans

Current Opinion in Microbiology, 1999
The adherent properties of Candida albicans blastoconidia and germ tubes have long been appreciated, but little is known about the mechanisms responsible for adherence. Recently, three genes, ALA1, ALS1 and HWP1, encoding proteins with adherent properties and motifs consistent with linkage to the beta-1, 6-glucan of C. albicans cell walls have provided
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Prediction and molecular insights into fungal adhesins and adhesin like proteins

Computational Biology and Chemistry, 2019
Adhesion is the foremost step in pathogenesis and biofilm formation and is facilitated by a special class of cell wall proteins known as adhesins. Formation of biofilms in catheters and other medical devices subsequently leads to infections. As compared to bacterial adhesins, there is relatively less work for the characterization and identification of ...
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Adhesins of pathogenic Yersiniae

Bacteriology, 2020
The genus Yersinia includes 26 species, three of which are pathogenic to humans: Yersinia enterocolitica and Yersinia pseudotuberculosis, which cause yersiniosis and pseudotuberculosis, infections with mainly gastrointestinal symptoms, and Yersinia pestis, the causative agent of plague.
A.S. Trunyakova   +2 more
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Surface Adhesins of Staphylococcus aureus

2006
An important facet in the interaction between Staphylococcus aureus and its host is the ability of the bacterium to adhere to human extracellular matrix components and serum proteins. In order to colonise the host and disseminate, it uses a wide range of strategies, the molecular and genetic basis of which are multifactorial, with extensive functional ...
Simon R, Clarke, Simon J, Foster
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Anti-Adhesins of Streptococcus Sobrinus

1996
Several members of the genus Streptococcus seem to be able to elaborate surface lectins. The oral streptococci have been reported to bind sialic acid ( S. sanguis) and α-glucans (Gibbons and Fitzgerald 1969). The organisms capable of binding α-glucans include S. cricetus and S. sobrinus. A few members of the highly cariogenic S. mutans also can complex
Q, Wang   +3 more
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Adhesins of Bartonella spp.

2011
Adhesion to host cells represents the first step in the infection process and one of the decisive features in the pathogenicity of Bartonella spp. B. henselae and B. quintana are considered to be the most important human pathogenic species, responsible for cat scratch disease, bacillary angiomatosis, trench fever and other diseases.
O’Rourke, F.   +4 more
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