Results 61 to 70 of about 3,215,770 (308)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The co‐effect of microstructures and mucus on the adhesion of abalone from a mechanical perspective
Biosurface and Biotribology, 2021 Reliable and reversible adhesion underwater is challenging due to the water molecules and weak layers of contaminants at the contact interface, which requires to deepen the understanding of wet adhesion of biological surfaces.
Jing Li +4 more
doaj +1 more source
, 2010 Human hands sweat in different circumstances and the presence of sweat can alter the friction between the hand and contacting surface. It is, therefore, important to understand how hand moisture varies between people, during different activities and the ...
Carre, M.J. +4 more
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Modelling adhesion-independent cell migration [PDF]
, 2020 A two-dimensional mathematical model for cells migrating without adhesion capabilities is presented and analyzed. Cells are represented by their cortex, which is modelled as an elastic curve, subject to an internal pressure force.
Jankowiak, Gaspard +4 more
core +5 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Friction and Wear in Nanoscratching of Single Crystals: Effect of Adhesion and Plasticity
Nanomaterials, 2022 Friction and wear are two main tribological behaviors that are quite different for contact surfaces of distinct properties. Conventional studies generally focus on a specific material (e.g., copper or iron) such that the tribological result is not ...
Jianqiao Hu, Qinglei Zeng
doaj +1 more source
A Test of the Adhesion Approximation for Gravitational Clustering [PDF]
, 1993 We quantitatively compare a particle implementation of the adhesion approximation to fully non--linear, numerical nbody simulations. Our primary tool, cross--correlation of nbody simulations with the adhesion approximation, indicates good agreement ...
Melott, A. L. +2 more
core +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Research and Improvement of Adhesion Utilization Control for HXD1C Locomotive
机车电传动, 2011 To settle several problems of locomotive HXD1C from actual operation on Lanzhou railway line, improved adhesion utilization control software for the locomotive was presented.
张建伯, 曾云
doaj