Results 151 to 160 of about 4,344,008 (259)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Evaluation of shear bond strength and adhesive remnant index of ceramic brackets using one-step self-adhesive composite resin [PDF]
Egyptian Orthodontic Journal, 2013 Essam Abdallah +3 more
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Evaluation of the Shear Bond Strength and Adhesive Remnant Index in Debonding of Stainless Steel Brackets Assisted with Nd:YAG Laser Irradiation. [PDF]
Front Dent, 2019 Nasiri M +7 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
Shear bond strength of deciduous and permanent bovine enamel
, 2011 The use of bovine teeth as a substitute for human enamel has been proposed for dental studies. The aim of this study was to determine the shear bond strength and Adhesive Remnant Index (ARI) of deciduous and permanent bovine teeth.
SCRIBANTE, ANDREA +3 more
core
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
“Effects of a Fluoride Containing Casein Phosphopeptide-Amorphous Calcium Phosphate Complex on Shear Bond Strength and Adhesive Remnant Index of Teeth Eroded by Different Beverages: An In-Vitro Study” [PDF]
INTRODUCTION- One of the most commonly encountered complications that we come across during orthodontic treatment is loosening of brackets or bond failure.
Rohan S. Hattarki, Ann Benzy
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