Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network [PDF]
An evidence-weighted functional-linkage network of human genes reveals associations among diseases that share no known disease genes and have dissimilar phenotypes.
Bolan Linghu +4 more
core +3 more sources
Necrotising Soft Tissue Infections: A Single Center's Case Series
ABSTRACT Necrotising soft tissue infection (NSTI) is a progressive disease with a time‐dependent prognosis; if not promptly treated, it can lead to significant morbidity as well as mortality. Early and aggressive surgical treatment is mandatory for appropriate management. This study reports the diagnostic and therapeutic pathway, surgical treatment and
Francesca Toia +6 more
wiley +1 more source
Cost-Effectiveness Of Treatments For Mild-To-Moderate Obstructive Sleep Apnea In France [PDF]
International audienceObjectives: Untreated obstructive sleep apnea-hypopnea syndrome (OSAHS) is associated with excessive daytime sleepiness, increased risk of cardiovascular (CV) disease, and road traffic accidents (RTAs), which impact survival and ...
Clementz, Marine +9 more
core +4 more sources
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Adriana Abizanda Saro +86 more
wiley +1 more source
Characterization of a mycovirus associated with the brown discoloration of edible mushroom, [PDF]
Background A mycovirus previously identified in brown discolored fruiting bodies of the cultivated mushroom Flammulina velutipes was characterized. We tentatively named the virus the F. velutipes browning virus (FvBV).
Sunagawa Masahide, Magae Yumi
core +1 more source
Outcome and Toxicity Profile of Stereotactic Body Radiation Therapy for Adrenal Tumours in Dogs
ABSTRACT Stereotactic body radiation therapy (SBRT) has become a non‐invasive alternative option for canine adrenal tumours with high surgical risks; however, its clinical benefits and risks are still to be fully understood. The goal of this multi‐institutional retrospective study was to describe the clinical outcome and safety of SBRT for the ...
Lily Thorsen +9 more
wiley +1 more source
HEART UK Consensus Statement on Lipoprotein(a) - a call to action [PDF]
Lipoprotein(a), Lp(a), is a modified atherogenic low-density lipoprotein particle that contains apolipoprotein(a). Its levels are highly heritable and variable in the population. This consensus statement by HEART UK is based on the evidence that Lp(a) is
Byrne, Chris D +16 more
core +3 more sources
Síndrome de Holmes - Adie: Relato de caso/ Holmes Syndrome - Adie: Case Report [PDF]
Camilla de Castro Dias Elias +11 more
openalex +1 more source
Ross syndrome: a case report [PDF]
Ross syndrome is a rare partial dysautonomic syndrome of unknown aetiology, characterized by segmental hypo/ anhidrosis associated with Holmes-Adie syndrome (tonic pupil and hypo/areflexia).
Bhattacharyya, R. +4 more
core +2 more sources
Ehlers-Danlos syndrome, hypermobility type, is linked to chromosome 8p22-8p21.1 in an extended Belgian family [PDF]
Joint hypermobility is a common, mostly benign, finding in the general population. In a subset of individuals, however, it causes a range of clinical problems, mainly affecting the musculoskeletal system.
Coucke, Paul +5 more
core +4 more sources

