Results 241 to 250 of about 261,601 (310)

Gastric motility and its association with adiposity and metabolic health in a cohort of Sri Lankan office workers. [PDF]

World J Gastrointest Pathophysiol
Basnayake PI, Kottahachchi D, Chandran DS, Medagoda K, Devanarayana NM.   +4 more
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Cardiometabolic Index, BMI, Waist Circumference, and Cardiometabolic Multimorbidity Risk in Older Adults. [PDF]

Geriatrics (Basel)
Kunutsor SK, Laukkanen JA.
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

A comparative analysis of anthropometric indices for identifying prediabetes in US adults: results from NHANES 2021-2023. [PDF]

Prev Med Rep
Chen X, Yan L, Yang J, Yang S.
europepmc   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Associations of early-adulthood adiposity with breast parenchymal tissue complexity within premenopausal women. [PDF]

Breast Cancer Res
Das Gupta S, Getz K, Hernandez Lopez J, Bennett DL, Toriola AT, Gastounioti A.   +5 more
europepmc   +1 more source

Association of Body Fat Percentage, Body Mass Index, and Waist Circumference With Hemodynamics: Insights From a Healthy Adult Population. [PDF]

Cureus
Sharma A, Sekhon S, Sandhu JS.
europepmc   +1 more source

Body Composition Changes and Their Associations with Physical Activity and Screen Time in a Sample of Italian Early Adolescents over a 3-Year Period. [PDF]

Children (Basel)
Gualdi-Russo E, Toselli S, De Luca F, Mazzoni G, Mandini S, Masotti S, Zaccagni L.   +6 more
europepmc   +1 more source