Results 171 to 180 of about 42,671 (271)

Sex differences in blood pressure and physical activity among socioeconomically vulnerable Portuguese schoolchildren aged 6 to 10 years: insights from the BeE-school Project. [PDF]

BMC Pediatr
Leite N, Tadiotto MC, Duarte A, Augusto C, Silva MJ, Brand C, Mota J, Pereira B, Rosário R.   +8 more
europepmc   +1 more source

Discovery and fine-mapping of adiposity loci using high density imputation of genomewide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium [PDF]

, 2017
Borecki, Ingrid B, et al.,, Feitosa, Mary F, Rao, D. C., Wojczynski, Mary K   +4 more
core   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Exercise FITT-V during pregnancy: dose-dependent reduction in infant cellular lipid content and whole body fat. [PDF]

J Appl Physiol (1985)
Claiborne A, Jevtovic F, Biagioni EM, Rossa L, Ollmann C, Zheng D, Strom C, Wisseman B, McDonald S, Newton E, Mouro S, deVente J, Kelley GA, Houmard JA, Broskey NT, May LE.   +15 more
europepmc   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Mediator role of physical activity in the relationship between anthropometric indicators and blood pressure in children with normal weight and children with overweight/obesity. [PDF]

BMC Public Health
Tadiotto MC, Leite N, Brand C, Duarte A, Augusto C, Silva MJ, Mota J, Pereira B, Rosário R.   +8 more
europepmc   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Bone and body composition by DXA in girls with precocious puberty, premature thelarche, and prepubertal controls. [PDF]

J Endocr Soc
Fava D, Casirati A, Angelelli A, Calevo MG, Pepino C, Pepe A, Maiorano NG, Acquarone L, Repetto A, Santucci C, Caridi C, Tedesco C, Napoli F, Allegri AEM, Patti G, Gastaldi R, Panciroli M, Naim A, Maghnie M, Di Iorgi N.   +19 more
europepmc   +1 more source

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source