Results 231 to 240 of about 2,087,550 (284)

Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions

Advanced Science, EarlyView.
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou, Taek Kang, Jie Chen, Yesh Doctor, Jocelyn G Camposagrado, Yiorgos Makris, Alexander Pertsemlidis, Leonidas Bleris   +7 more
wiley   +1 more source

Spatially Informed Graph Structure Learning Extracts Insights from Spatial Transcriptomics. [PDF]

Adv Sci (Weinh)
Nie W, Yu Y, Wang X, Wang R, Li SC.
europepmc   +1 more source

Choroid Plexus Fibroblast–ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury

Advanced Science, EarlyView.
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao, Xiaoming Guo, Sixuan Tian, Huaping Huang, Caidi Ying, Junjie Wang, Jiahao Zhang, Jun Lin, Anwen Shao, Jingyu Wang, Yuan Hong   +10 more
wiley   +1 more source

MPAT: Modular Petri Net Assembly Toolkit. [PDF]

SoftwareX
Chiaradonna S, Jevtić P, Sterner B.
europepmc   +1 more source

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

EdgeHOG: fine-grained ancestral gene order inference at tree-of-life scale

Bernard C, Nevers Y, Karampudi NBR, Gilbert KJ, Train C, Vesztrocy AW, Glover N, Altenhoff A, Dessimoz C.   +8 more
europepmc   +1 more source

Prediction of reproductive and developmental toxicity using an attention and gate augmented graph convolutional network. [PDF]

Sci Rep
Lee SH, Choi E, Park J, Yoon S, Song MH, Lee JY, Seo J, Shin SK, Lee SH, Oh HB.   +9 more
europepmc   +1 more source

A bidirectional reversible and multilevel location privacy protection method based on attribute encryption. [PDF]

PLoS One
Hu Z, Hu K, Hasan MMK.
europepmc   +1 more source

GraSp-PSN: A web server for graph spectra based analysis of protein structure networks. [PDF]

Curr Res Struct Biol
Gadiyaram V, Prabantu VM, Manjaly AA, Muthiah A, Vishveshwara S.   +4 more
europepmc   +1 more source