Results 131 to 140 of about 174,987 (258)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Shielding of the total electric field above building platforms near UHVDC transmission lines by grounded metal mesh. [PDF]

Sci Rep
Liao Z, Zhang J, Zhang Y, Gan Z, Zhao J, Wan B.   +5 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Symmetry-directed complex tessellation of irregular polygons from a single molecular precursor. [PDF]

Chem Sci
Zhai W, Ou Z, Chen Y, Zang H, Guo D, Li J.   +5 more
europepmc   +1 more source

Development of fragility curve for buildings adjacent to slope

, 2016
Previous earthquake provided evidence of significant effects of topographic irregularities on seismic site response. It is remarkable that the importance of topographical effects, moreover, has been discussed by a series of analytical and numerical studies.
openaire   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A Method for 3D Building Individualization Integrating SAMPolyBuild and Multiple Spatial-Geometric Features. [PDF]

Sensors (Basel)
Cao L, Cheng Y, Zhang Z, Zhu G, Ma K, Xu X.   +5 more
europepmc   +1 more source

DYNAMIC BEHAVIOR OF ADJACENT BUILDINGS CONNECTED WITH DAMPERS

, 2015
Summary This paper analyzes the properties of the dynamic behavior of two adjacent buildings of different height connected by viscous/viscoelastic dampers located at the top of the shortest building. The adjacent structures are described through a continuum approach as two interconnected uniform shear beams.
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A geostatistical imputation of first floor elevation data for mapping flood vulnerability. [PDF]

Nat Hazards (Dordr)
Raja P, Li Y, Gong J.
europepmc   +1 more source