Results 51 to 60 of about 174,987 (258)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Three-Dimensional Simulation of Seismic Structure–Soil–Structure Interaction for Mid-Rise Buildings near Dense Shallow Sloping Soils Under the Impact of 6 February 2023 Kahramanmaraş-Pazarcık Earthquake

open access: yesBuildings
During a seismic movement, each wave field incoming to a foundation by reflecting from the surroundings causes amplification. Therefore, the seismic response of any building is affected by both the topography and the adjacent building. In this study, the
Hamza Güllü, Ozan Natur
doaj   +1 more source

Permanent excavation interaction and adjacent building under earthquake (Case study: Entrance ramp of the city train and hamyari-shahrdari building) [PDF]

open access: yesJournal of Structural and Construction Engineering, 2019
Deep excavation have a direct effect on stresses and strains of surrounding soil, and it leads to the change in static and dynamic response of adjacent structures of the excavation.
Jahangir Khazaei, Afshin Ghobadian
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Collision Risk Analysis of Base-isolation Retrofitted Adjacent Buildings Connected by a Corridor Bridge

open access: yes工程科学与技术, 2019
Two adjacent buildings connected by a corridor bridge were retrofitted with the base isolation technology. Considering different seismic wave incidence angles, this paper calculated seismic responses of the buildings under bidirectional earthquakes using
Kaoshan DAI   +3 more
doaj  

Sensitivity Analysis and Optimization of Facade Design to Improve Daylight Performance of Tropical Classrooms with an Adjacent Building

open access: yesJournal of Daylighting
This study examines the daylighting performance of a classroom with bilateral opening typology and an adjacent building on one side. The openings are located on the east and west sides of the classroom, with the adjacent building situated on the west ...
Atthaillah   +2 more
doaj   +1 more source

Three-dimensional finite element analysis of effects of foundation underpinning on deformation control of existing buildings adjacent to a deep excavation

open access: yesYantu gongcheng xuebao, 2017
The excavation of Dingding Bund is adjacent to an existing heritage architecture. As the pit is as deep as 20 m and the heritage architecture is only about 3 m away from the excavation, foundation underpinning is adopted in order to minimize the ...
LI Jing 1, 2, XU Zhong-hua 1, 2, WANG Wei-dong 1, 2
doaj   +1 more source

Experiments on Coupled Technique for Adjacent Similar Buildings [PDF]

open access: yesInternational Journal of Engineering, 2020
Increasing the population, urbanization has led to the rapid construction of buildings. Due to space constraints and an increase in land cost, these buildings are built too close to each other and can cause damage under dynamic actions such as earthquakes.
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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