Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Radiographic and Clinical Adjacent Segment Disease After Posterior Instrumented Fusion for Traumatic Thoracolumbar and Lumbar Vertebral Fractures. [PDF]
Baz AB +5 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Systemic inflammation and adjacent segment disease after lumbar fusion: the importance of biomarker timing. [PDF]
Abudayeh A, Fishchenko I.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Does congenital cervical fusion predispose to adjacent segment degeneration? A retrospective cohort study. [PDF]
Liu Y, Han N, Liu WG, Song AJ, Liu LD.
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Thoracic medial branch peripheral nerve stimulation for adjacent segment pain in a patient with a long construct fusion: a case report. [PDF]
Wanner LK +3 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Biomechanical effects of cortical bone trajectory and hybrid CBT-TT fixation on fusion-site mechanics and adjacent segment loading: a finite element study. [PDF]
Hu P, Lei J, Wu F, Liu Z, Wei F, Liu X.
europepmc +1 more source

