Results 61 to 70 of about 18,187 (261)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Morphological and Semantic Types of Old English Lost Adjectives
Miscelánea: A Journal of English and American Studies, 2014 The aim of this article is to provide a morphological and semantic analysis of the ca. 4,800 Old English adjectives that, having got lost throughout linguistic evolution, are not included in the Oxford English Dictionary.
Luisa Fidalgo Allo
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
When are adjectives raisers? Tough to get it
Bucharest Working Papers in Linguistics, 2007 This article deals with some unsolved problems raised by tough-adjectives in Romance languages. We present some new data from some Romance languages (Romanian, French, Italian) supporting a raising analysis, and we argue that in these languages, unlike ...
Ion Giurgea, Elena Soare
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Baltistica, 2011 The article deals with the historical development of the accentuation of suffixless (root), *-ьnъ and *-ъkъ adjectives. Their development is analyzed in detail from their Proto-Slavic origin to their modern reflexes in Štokavian, Čakavian and Kajkavian ...
Mate Kapović
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Bare adjectives as syncretic forms
Borealis: An International Journal of Hispanic Linguistics, 2014 The goal of this paper is to discuss the categorical status and semantic properties of the so-called adjective adverbs (ngrale 2009: 2295-2301). As these forms are actually real adjectives lacking productive gender and number agreement, we will call them
Avel·lina Suñer, Angela Di Tullio
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source