Results 181 to 190 of about 57,717 (299)

Use of a large language model integrated within the electronic medical record for the evaluation of surgical site infections - Northern California, 2025. [PDF]

open access: yesInfect Control Hosp Epidemiol
Miranti E   +9 more
europepmc   +1 more source

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

open access: yesEpilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan   +14 more
wiley   +1 more source

Gold standard assessment of delirium severity in patients with dementia: Evaluation of an expert panel adjudication process. [PDF]

open access: yesJ Alzheimers Dis
Boockvar KS   +11 more
europepmc   +1 more source

Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta‐analysis from ILAE Epilepsy Surgery Networks Task Force

open access: yesEpilepsia, EarlyView.
Abstract Intracranial electroencephalographic (iEEG) connectivity analysis is a promising method to localize epileptic networks and guide surgical planning in focal drug‐resistant epilepsy. Despite numerous studies exploring its utility, the added value of iEEG connectivity over standard clinical presurgical evaluation remains unclear.
Nishant Sinha   +15 more
wiley   +1 more source

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

open access: yesEpilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini   +15 more
wiley   +1 more source

High‐frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development

open access: yesEpilepsia, EarlyView.
Abstract Objective The development of posttraumatic epilepsy after traumatic brain injury (TBI) is potentially identifiable by measuring biomarkers of epileptogenesis, namely pathological high‐frequency oscillations (pHFOs). pHFOs are promising candidates, but it remains uncertain whether they can be detected early after TBI in clinical settings.
Kseniia Kriukova   +48 more
wiley   +1 more source

Improving retrospective ARDS case-finding using a simple 72-h physiologic persistence rule. [PDF]

open access: yesIntensive Care Med Exp
Marshall DC   +5 more
europepmc   +1 more source

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