Results 71 to 80 of about 38,344 (265)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Enhancing the Relation between the Individuals and Society through Interactive Outdoor Communal Spaces in Public Buildings: An Analytical Study for Multi-Commercial Complexes [PDF]

open access: yesMSA Engineering Journal
The “Human-Centered Planning” approach, as outlined by many researchers, has been utilized by designers and planners to evaluate individuals’ satisfaction with urban environments.
Kanzy Elhalwagy   +1 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

SUPPORTING ONLINE ADJUNCT FACULTY: A VIRTUAL MENTORING PROGRAM

open access: yesOnline Learning, 2019
Because of growing demand for online courses, staffing and faculty support issues can become major obstacles to growth and instructional quality. In 2004, Florida Community College at Jacksonville (FCCJ) was awarded an Effective Practices Award at the ...
Maria Puzziferro-Schnitzer   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Consequences of pair-merge (at the interfaces)

open access: yesAnuario del Seminario de Filología Vasca "Julio de Urquijo", 2007
The goal of this paper is to explore the basic properties of adjuncts and some of the well-known puzzles these dependents pose for syntactic theorizing within the scenario provided by the Minimalist Program (cf. Chomsky 1995 through the present).
Aritz Irurtzun, Ángel J. Gallego
doaj   +1 more source

Quillen adjunctions induce adjunctions of quasicategories

open access: yes, 2015
We prove that a Quillen adjunction of model categories (of which we do not require functorial factorizations and of which we only require finite bicompleteness) induces a canonical adjunction of underlying quasicategories.
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Emai's Variable Coding of Adjuncts

open access: yesLinguistic Discovery, 2014
This paper examines the morphosyntactic character of clauses containing adjuncts in Emai (Edoid and West Benue Congo). In clauses differing as to discourse function, adjunct coding is variable.
Ronald P. Schaefer, Francis O. Egbokhare
doaj   +1 more source

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