Results 91 to 100 of about 1,606,860 (312)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Thomas V Merluzzi,1 MaryAnn Martinez Sanchez2 1Department of Psychology, University of Notre Dame, Notre Dame, IN, 2Pima Community College, Tucson, AZ, USA Introduction: Recent reviews have reinforced the notion that having a supportive spouse can help ...
Merluzzi TV, Martinez Sanchez M
doaj
Background: Despite a long interest in the historical fertility transition, there is still a lack of knowledge about disaggregated patterns that could help us understand the mechanisms behind the transition.
Martin Dribe, Michel Oris, Lucia Pozzi
doaj +1 more source
Exploring positive adjustment in people with spinal cord injury. [PDF]
This study explored adjustment in people with spinal cord injury; data from four focus groups are presented. Thematic analysis revealed four themes, managing goals and expectations, comparison with others, feeling useful and acceptance, showing ...
Donovan-Hall, M +13 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The first Report of the Deputies of the Group of Ten and the parallel Report of the IMF from 1964 reached unanimous consensus on the basic deficiencies of the international monetary system and the general nature of the revolutionary reforms required for ...
R. TRIFFIN
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Elaborasi Penyusunan Laporan Keuangan Konsolidasi ke Dalam Nilai Syariah Islam
This study aimed to obtain a design of the process of preparing the consolidated financial statements associated with shariah values in Islam, especially the value of fairness and honesty.
Bambang Waluyo, Ali Masjono
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

