Results 151 to 160 of about 1,674,504 (263)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Profiles of identity centrality and psychological adjustment among Hispanic/Latine sexual minoritized emerging adults. [PDF]

J Res Adolesc
Cruz B, Meca A, Peña JD, Graelles A, Scott SB.   +4 more
europepmc   +1 more source

Interrelationships Between Labor and Capital Adjustment Decisions [PDF]

This paper intends to provide empirical evidence on the interrelationship between employment and capital adjustment decisions. A fixed-effect logit model is employed to estimate this interrelationship using a data set of large Italian firms. Whereas some
Edlira Narazani
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Patterns of Current Account Adjustment – Insights from Past Experience [PDF]

The paper examines episodes of current account adjustment in individual economies. A central finding is that these episodes are very divergent and can be usefully classified, on the basis of cluster analysis, in three groups.
Bernardina Algieri, Thierry Bracke
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Occlusal Adjustment in Free-End Implant-Supported Restorations: Digital Scans Versus Conventional Impressions With Full- and Half-Arch Techniques. [PDF]

Clin Exp Dent Res
Nakhaei M, Dashti H, Shahri A, Rahmani M, Kazemian A, Sabzevari S, Rezaee M.   +6 more
europepmc   +1 more source

Education for life adjustment : what is it?

, 1952
"Life Adjustment is an educational program which attempts to help all youth meet life realistically. It aims to develop good home members, good workers, and good citizens.

core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Two-Stage Estimation for Causal Inference Involving Semi-Continuous Exposures. [PDF]

Stat Med
Wang X, Cook RJ, Zhu Y, Akkaya-Hocagil T, Carter RC, Jacobson SW, Jacobson JL, Ryan LM.   +7 more
europepmc   +1 more source