Association between segmental and whole-body phase angle from bioelectrical impedance analysis and the physical function in community-dwelling older adults. [PDF]
Ayala-Martinez C +6 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
An integrated method for railway fastener defect detection and geometric parameter measurement using 3D line laser sensor. [PDF]
Yuan X, Liu W, Ma Y, Wang Y, Liu B.
europepmc +1 more source
Speed of adjustment of capital structure: empirical study
We analyze the impact of firm-specific characteristics as well as economic factors on the speed of adjustment to the target debt ratio. Using different methods, we document speeds of adjustment ranging from 14.4% to 37%.
Lopes, Natalia Cristina
core
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Dynamic analysis and driving performance verification of multi-functional electric tracked vehicles for greenhouses in hilly and mountainous areas. [PDF]
Zeng L +8 more
europepmc +1 more source
External Debt, Adjustment, and Growth [PDF]
High ratios of external debt to GDP in selected Asian countries have contributed to the initiation, propagation, and severity of the financial and economic crises in recent years, reflecting runaway fiscal deficits and excessive foreign borrowing by the ...
Delano Villanueva, Roberto S. Mariano
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Digital Handwriting Kinematics and Physical Performance According to Pentagon-Copy Performance in Community-Dwelling Older Adults: Cross-Sectional Study. [PDF]
Ferrer-Ramos P +4 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source

