Results 201 to 210 of about 495,599 (268)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Nano-adjuvants enhance the immunogenicity and safety of infectious bursal disease virus vaccines: a comprehensive review. [PDF]

Front Immunol
Asif TA, Ji P, Qiao X, Yang Q, Jiang D, Zhang G.   +5 more
europepmc   +1 more source

KRAS and BRAF mutations modify adjuvant chemotherapy outcomes in early stage colorectal cancer. [PDF]

NPJ Precis Oncol
Wankhede D, Rodriguez MJU, Edelmann D, Kloor M, Bläker H, Brobeil A, Roth W, Brenner H, Hoffmeister M.   +8 more
europepmc   +1 more source

Real-world use of neratinib as extended adjuvant therapy in HER2-positive early-stage breast cancer: a multicentre study in mainland China and Hong Kong. [PDF]

Breast
Abudureheiyimu N, Jia Y, Peng Z, Shi Y, Liu Q, Wang H, Zhou Y, Wang H, Wang K, Hu H, Liu Z, Chen W, Ng TY, Guo Z, Ren Z, Zhen H, Fan Y, Xu B.   +17 more
europepmc   +1 more source

Endometrial Cancer Recurrence Risk Following Robotic Hysterectomy. [PDF]

Curr Oncol
Zhu S, Wiebe E, Frerichs H, Ghosh S, Gill J, Habsi ZA, Beruar A, Pin S.   +7 more
europepmc   +1 more source

Adjuvant stereotactic pancreatic radiotherapy (SPARTA trial): interim safety analysis of an ongoing phase II single center prospective study. [PDF]

Radiat Oncol
Massaro M, Comito T, Franzese C, Teriaca MA, Loi M, Badalamenti M, Franceschini D, Ilieva MB, Marini B, Lo Faro L, Vernier V, Tomatis S, Gallo P, Bozzarelli S, Rimassa L, Bonifacio C, Carrara S, Capretti GL, Santoro A, Zerbi A, Scorsetti M.   +20 more
europepmc   +1 more source

Expression of Concern: Platinum-based adjuvant therapy was efficient for triple-negative breast cancer: a meta-analysis from randomized controlled trials. [PDF]

Bioengineered
europepmc   +1 more source