Results 271 to 280 of about 765,314 (335)

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

Escalation and De-Escalation of Adjuvant Radiotherapy in Early Breast Cancer: Strategies for Risk-Adapted Optimization. [PDF]

Cancers (Basel)
Gruber G.
europepmc   +1 more source

Laterally positioned flap with connective tissue graft to treat deep isolated gingival recessions in the mandibular anterior region: A retrospective case series with 10‐year follow‐up

Clinical Advances in Periodontics, EarlyView.
ABSTRACT Background To evaluate the efficacy and long‐term clinical outcomes of the one‐stage procedure for covering isolated deep gingival recessions (GRs) in the mandibular anterior region employing a laterally positioned flap (LPF) with a connective tissue graft (CTG), with a retrospective case series.
Lucrezia Parma‐Benfenati, Stefano Parma‐Benfenati   +1 more
wiley   +1 more source

Fat Grafting and Prepectoral Prosthetic Reconstruction with Polyurethane-Covered Implants: Protective Role against Adjuvant Radiotherapy. [PDF]

J Clin Med
Barone Adesi L, Taraschi F, Macrì G, Scardina L, Di Leone A, Franceschini G, Salgarello M.   +6 more
europepmc   +1 more source

Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma

ChemMedChem, Accepted Article.
Glioblastoma (GBM) is the most common and aggressive malignant grade IV brain tumour and is one of the most difficult types of brain cancer to treat with a high incidence of resistance to traditionally used chemotherapeutics. Pyrazolopyrimidinones are fused nitrogen‐containing heterocyclic systems which are a scaffold in several bioactive drugs and ...
Kate Byrne, Natalia Bednarz, Ciara McEvoy, John C. Stephens, James F. Curtin, Gemma Kinsella   +5 more
wiley   +1 more source

Safety of the Breast Cancer Adjuvant Radiotherapy in Ataxia-Telangiectasia Mutated Variant Carriers. [PDF]

Cancers (Basel)
Bensenane R, Beddok A, Lesueur F, Fourquet A, Warcoin M, Le Mentec M, Cavaciuti E, Le Gal D, Eon-Marchais S, Andrieu N, Stoppa-Lyonnet D, Kirova Y.   +11 more
europepmc   +1 more source

Deciphering the transcriptomic landscape of early HR+/HER2− breast cancer in very young women

Cancer Communications, EarlyView.
Iris Garrido‐Cano, Marta Tapia, Juan Carbonell, Carlos Peña, Sandra Torres‐Ruiz, Anna Ágreda‐Roca, Ana Lameirinhas, Cristina Tebar, Octavio Burgués, Cristina Hernando, Ana Lluch, Fara Brasó‐Maristany, Aleix Prat, Begoña Bermejo, María Teresa Martínez, Juan Miguel Cejalvo   +15 more
wiley   +1 more source

Enhancing positioning accuracy in adjuvant radiotherapy for left breast cancer using cervical-thoracic integrated bracket combined with deep inspiration breath holding. [PDF]

Thorac Cancer
Wan B, Liu Y, Ge Y, Liu F, Zhao R, Li T, Zhang Y, Zhang W, Huan F, Yang X, Hui Z.   +10 more
europepmc   +1 more source

Thyroblastoma in Pregnancy: Expanding the Cytomorphological Spectrum of a Novel DICER1‐Associated Entity, a Case Report and Literature Review

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction Thyroblastoma is a rare, aggressive thyroid neoplasm newly classified in the 2022 WHO Classification of Endocrine Tumors. It is characterized by embryonal, multilineage morphology and DICER1 mutations. Fewer than 15 well‐characterized cases have been reported, with limited cytological descriptions.
R. Razack, A. C. van Wyk, P. T. Schubert, D. Pelletier, W. D. Foulkes, C. Njovu, W. Conradie, F. Hoosain   +7 more
wiley   +1 more source

Effectiveness of Myofascial Release Compared to Manual Lymphatic Drainage in Reducing Post-Treatment Shoulder Pain and Stiffness Among Patients Who Underwent Breast Cancer Surgery and Adjuvant Radiotherapy: <i>Randomised controlled trial</i>. [PDF]

Sultan Qaboos Univ Med J
Vijayakumar C, Jain A, Kalaranjani M, Kumbhar US, Kumar N, Sreenath GS.   +5 more
europepmc   +1 more source