Results 111 to 120 of about 573,829 (353)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Venous ulcer healing treated with conventional therapy and adjuvant laser: is there a difference?

open access: green, 2022
Viviane Maria Osmarin   +4 more
openalex   +1 more source

Adjuvant Therapy [PDF]

open access: yesSuizo, 2020
Katsuhiko UESAKA   +4 more
openaire   +3 more sources

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

Long-term efficacy and safety of letrozole for the adjuvant treatment of early breast cancer in postmenopausal women: a review

open access: yesTherapeutics and Clinical Risk Management, 2009
Alain MonnierInstitut Régional Fédératif du Cancer (IFRC), Centre Hospitalier Belfort-Montbéliard, Montbéliard, FranceAbstract: Aromatase inhibitors (AIs) are becoming more widely used than tamoxifen
Alain Monnier
doaj  

Real-world efficacy of postoperative adjuvant EGFR-TKI therapy for stage IA2-IA3 lung adenocarcinoma with high-risk pathological factors

open access: yesWorld Journal of Surgical Oncology
Background The role of EGFR-TKIs as adjuvant therapy for stage IA lung adenocarcinoma after surgery remains controversial. Though 5-year OS of stage IA patients reaches 88%, the 5-year DFSs of IA1, IA2, and IA3 vary a lot, 88.2%, 73.6% and 64.5 ...
Sida Lu   +6 more
doaj   +1 more source

Update on Adjuvant Chemotherapy for Early Breast Cancer

open access: yesBreast Cancer: Basic and Clinical Research, 2014
Breast cancer is the second most common cancer in women worldwide. Although most women are diagnosed with early breast cancer, a substantial number recur due to persistent micro-metastatic disease. Systemic adjuvant chemotherapy improves outcomes and has
Murtuza M. Rampurwala   +2 more
doaj   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai   +13 more
wiley   +1 more source

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