Results 281 to 290 of about 2,696,581 (351)

Treatment of metastatic lung cancer via inhalation administration of curcumin composite particles based on mesoporous silica.

European Journal of Pharmaceutical Sciences, 2019
Curcumin attracted attention due to its promising anti-cancer properties and safety performance. However, its poor aqueous solubility and low bioavailability have to be overcome before it goes into clinic use.
Wenqiang Su, Tongxin Wei, Manqi Lu, Zhiping Meng, Xuanyu Chen, Jie Jing, Junsong Li, Weiwei Yao, Huaxu Zhu, Tingming Fu   +9 more
semanticscholar   +1 more source

Prehospital administration of inhaled metaproterenol

Annals of Emergency Medicine, 1990
We conducted a study of the prehospital use of inhaled metaproterenol. DESIGN, SETTING, TYPE OF PARTICIPANTS, AND INTERVENTIONS: Advanced life support (ALS) providers were trained with a standardized curriculum to identify patients likely to benefit from prehospital inhaled metaproterenol administration.
D R, Eitel, S A, Meador, R, Drawbaugh, D, Hess, N K, Sabulsky, R, Bernini   +5 more
openaire   +2 more sources

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery.

Journal of Visualized Experiments, 2018
Intranasal administration has been reported to be a potential pathway for nose-to-brain delivery of therapeutic agents that circumvents the blood-brain barrier.
T. Kanazawa, Mitsuyoshi Fukuda, N. Suzuki, Toyofumi Suzuki   +3 more
semanticscholar   +1 more source

Inhalation therapy devices for the treatment of obstructive lung diseases: the history of inhalers towards the ideal inhaler.

European journal of internal medicine, 2020
Inhalation therapy allows conveying drugs directly into the airways. The devices used to administer inhaled drugs play a crucial role in the management of obstructive lung diseases such as asthma and chronic obstructive pulmonary disease (COPD).
C. Sorino, Stefano Negri, A. Spanevello, D. Visca, N. Scichilone   +4 more
semanticscholar   +1 more source

Inhalation of Tetrandrine- hydroxypropyl-β-cyclodextrin Inclusion Complexes for Pulmonary Fibrosis Treatment.

Molecular Pharmaceutics, 2020
Pulmonary fibrosis (PF) is a kind of interstitial lung disease with the features of progressive and often fatal dyspnea. Tetrandrine (TET) is the major active constituent of Chinese herbal Stephania tetrandra S.
Wenqiang Su, Yinmei Liang, Zhiping Meng, Xuanyu Chen, Manqi Lu, Xingxing Han, Xiaomin Deng, Qichun Zhang, Huaxu Zhu, Tingming Fu   +9 more
semanticscholar   +1 more source

Paeonol loaded cyclodextrin metal-organic framework particles for treatment of acute lung injury via inhalation.

International journal of pharmaceutics, 2020
Administration of drugs via inhalation can overcome issues related to poor water solubility, low absorption or bioavailability associated with oral administration.
Haiyan Li, Jie Zhu, Cai-fen Wang, Wei Qin, Xiaoxiao Hu, J. Tong, Lin Yu, Guoqing Zhang, X. Ren, Zegeng Li, Jiwen Zhang   +10 more
semanticscholar   +1 more source

Administration of nebulised and inhaled medications

In Practice, 2018
![Graphic][1] Ben Harris qualified from the University of Cambridge in 2002. He spent seven years in private veterinary practice before completing a residency in small animal medicine at the University of Cambridge in 2012. He is a diplomate of the European College of Veterinary Internal Medicine and an RCVS Specialist in small animal internal ...
openaire   +1 more source

GSK256066, an Exceptionally High-Affinity and Selective Inhibitor of Phosphodiesterase 4 Suitable for Administration by Inhalation: In Vitro, Kinetic, and In Vivo Characterization

Journal of Pharmacology and Experimental Therapeutics, 2011
Oral phosphodiesterase (PDE) 4 inhibitors such as roflumilast have established the potential of PDE4 inhibition for the treatment of respiratory diseases.
C. Tralau-Stewart, R. Williamson, A. Nials, M. Gascoigne, J. Dawson, G. Hart, A. Angell, Y. Solanke, F. Lucas, Joanne O. Wiseman, P. Ward, L. Ranshaw, Richard Graham Knowles   +12 more
semanticscholar   +1 more source

The potential to treat lung cancer via inhalation of repurposed drugs.

Advanced Drug Delivery Reviews, 2018
Lung cancer is a highly invasive and prevalent disease with ineffective first-line treatment and remains the leading cause of cancer death in men and women.
Wing-Hin Lee, C. Loo, Maliheh Ghadiri, C. Leong, P. Young, D. Traini   +5 more
semanticscholar   +1 more source

Inhaled Bronchodilator Administration During Mechanical Ventilation

Respiratory Care, 2004
Inhaled bronchodilators are routinely administered to mechanically ventilated patients to relieve dyspnea and reverse bronchoconstriction. A lower percentage of the nominal dose reaches the lower respiratory tract in a mechanically ventilated patient than in a nonintubated subject, but attention to device selection, administration technique, dosing ...
openaire   +2 more sources