Results 41 to 50 of about 2,458,206 (306)

Transmucosal nasal drug delivery : systemic bioavailability of nasally applied midazolam [PDF]

, 2008
Transmucosal nasal drug delivery is a drug delivery option for challenging clinical situations where common drug administrations (e.g., intravenous, intramuscular, or oral) are inapplicable.
Suter-Zimmermann, Katja
core   +1 more source

How Important is Intravenous Fluid Administration to Patients Presenting to the Emergency Department and to Their Families?

Eurasian Journal of Emergency Medicine, 2018
Aim: Intravenous fluid administration is a frequently applied form of therapeutic service in emergency departments. This study aimed to determine the effect of intravenous fluid administration on patients’ and their relatives’ preference for emergency ...
Ozgur Tatli, Perihan Simsek, Ayla Gursoy, Murat Topbas, Vildan Ozer, Abdulkadir Gunduz   +5 more
doaj   +1 more source

Pharmacokinetics and tissue distribution of gentiopicroside following oral and intravenous administration in mice

, 2004
The pharmacokinetics and tissue distribution of Gentiopicroside (GPS), one of the major active components of the Gentiana species of medicinal plants, was studied following oral and intravenous administration in mice.
Wang, C.-H., Branford-White, C.J., White, K.N., Wang, Z., Bligh, S.W.A.   +4 more
core   +1 more source

Intravenous Fluid Administration and the Coagulation System

Frontiers in Veterinary Science, 2021
Intravenous fluid administration in veterinary patients can alter coagulation function by several mechanisms. Both crystalloid and colloid fluids cause hemodilution, reducing platelet count and plasma coagulation protein concentrations.
Corrin J. Boyd, Benjamin M. Brainard, Lisa Smart   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Evaluation of pharmacokinetics underlies the collaborated usage of lamivudine and oxymatrine in beagle dogs

Asian Journal of Pharmaceutical Sciences, 2016
Combinational therapy of lamivudine and oxymatrine has been employed in the battle against hepatitis B virus in clinical setting. However, the pharmacokinetic behavior of the drug or active metabolism in intravenous/oral co-administration regime is ...
Zhenbao Li, Lei Shang, Chang Liu, Panqin Ma, Chunnuan Wu, Wenjuan Zhang, Yinghua Sun, Yongjun Wang, Xiaohong Liu, Jin Sun   +9 more
doaj   +1 more source

Comparison of the effects of intramyocardial and intravenous injections of human mesenchymal stem cells on cardiac regeneration after heart failure [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Existing studies have demonstrated that intravenous and intramyocardial-administrated mesenchymal stem cells (MSCs) lead to tissue repair after cardiac disorders.
Behnaz Mokhtari, Nahid Aboutaleb, Donya Nazarinia, Mahin Nikougoftar, Seyed Mohammad Taghi Razavi Tousi, Mohammad Molazem, Mohammad-Reza Azadi   +6 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Pharmacokinetic studies of meloxicam after its intravenous administration in local goat (Capra hircus) of Assam [PDF]

, 2013
Aim: The aim of the present study was to determine the meloxicam concentrations in the plasma of goats at different time intervals after its administration by IV route and data were used to determine the different pharmacokinetic parameters and the ...
Abdul Rakeeb Wani, Rohini K. Roy, Dulal C. Roy, Ajmal Ashraf   +3 more
core   +2 more sources

Risk factors for linezolid-associated hyponatremia focused on differences between intravenous and oral administration: a single-center, retrospective study

Journal of Pharmaceutical Health Care and Sciences
Background Linezolid (LZD)-associated hyponatremia is a rare side effect, and no reports have compared intravenous and oral administration in relation to the development of hyponatremia.
Ryoji Takata, Masatoshi Taga, Hirofumi Nagai, Yoshihiro Nishita, Hironori Kobayashi, Nozomi Arakawa, Toru Imai, Yoshitsugu Iinuma, Togen Masauji   +8 more
doaj   +1 more source