Results 141 to 150 of about 908,314 (313)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Oral Administration of Lidocaine for Treatment of Obstinate Hiccup Caused by the Operation on the Cervical Spondylosis

open access: yesHuli yanjiu, 1996
一般认为呃逆是病理性呼吸反射,即由于突然吸气,横膈发生阵发性痉挛以及声门突然关闭,同时伴有呼气性肋间肌抑制,使肺内充气量减少,气道内气体上冲,产生通常所听到的打嗝声音。呃逆一般可自愈 ...
郭淑敏, 吴变梅
doaj  

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Safe administration of oral chemotherapy [PDF]

open access: yes, 2018
Administration and documentation of oral chemotherapy agents is a complex process involving multiple health care professionals to maximize patient adherence and safety. In 2016, the Oncology Nursing Society (ONS) in conjunction with the American Society
Comes, Julie
core  

The Case of a 40‐Year‐Old Man With New‐Onset Status Epilepticus in the Setting of HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 40‐year‐old man from Andhra Pradesh in India, while on regular antiretroviral treatment (ART) for long‐standing HIV infection presented with a 1‐day history of new‐onset status epilepticus. CT and MRI brain showed multifocal cerebral ring lesions, some of which demonstrated characteristic ‘hole‐with‐a‐dot’ sign.
Vadde Akhil, Ramachandiran Nandhagopal
wiley   +1 more source

Oral History Interview: John Kutzbach (0753) [PDF]

open access: yes, 2016
Interviewed by Robert LangeAbstract: Childhood and early education in Reedsburg, WI; The influence of family and teachers; Undergraduate education at the University of Wisconsin in the 1950s; Air Force ROTC training; Completion of a Master’s Degree at UW;
Lange, Robert, Kutzbach, John
core  

Chitosan-alginate capsules as oral delivery system for insulin: studies in vitro and in vivo

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2008
The aim of this study was to assess chitosan:alginate capsules as gastric resistant systems for oral administration of insulin. Chitosan:alginate capsules of insulin were tested in simulated gastric and intestinal media and in vivo. The capsules released
C. Bürger   +4 more
doaj  

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Analgesic Effect According to Administration Time for Oral Surgical Pain [PDF]

open access: yes, 2003
Background: Studies on the pain have been dealing with many different ways for last several centuries. Especially, many studies on efficacy of preemptive analgesia have been processed in different ways about various drugs, administration methods and ...
정영수
core  

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