Results 151 to 160 of about 9,194,937 (294)

METHODOLOGICAL APPROACHES IN REALIZING AND APPLYING COST-BENEFIT ANALYSIS FOR THE INVESTMENT PROJECTS [PDF]

Cost-benefit analysis represents the most frequent technique used for a rational allocation of resources. This modality of evaluating the expenditure programs is an attempt to measure the costs and gains of a community as a result of running the ...
Gligor Delia, Munteanu Valentin, Pantea Marius, Pelin Andrei   +3 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Yönetim Algısındaki Değişim: Yönetimde Özerk İnsan Unsuru

Mehmet Akif Ersoy Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2015
Devlet bir ülkede en üst ve en güçlü kurum olarak yürütme aracı olan yönetim sayesinde faaliyetlerini sürdüren canlı bir varlıktır. Ancak devleti soyut bir kavramdan somut bir gerçekliğe taşıyan unsur ise devlet çatısı altında yaşayan insanlardır ...
Hikmet Yavaş, Konur Demir
doaj  

A device for the drug-capsule administration into the rat stomach and its pharmacological application

, 1981
Shuichi Takeda, Takeshi Abe, Masamichi OTSUKA   +2 more
openalex   +2 more sources

Administration and Finance Division Newsletter, Nov. 2013 [PDF]

, 2012
San Jose State University, Administration and Finance Division
core   +4 more sources

ASSOCIATIVE AND VOLUNTARY PARTICIPATION: A PATH TO COMMUNITY DEVELOPMENT [PDF]

In this paper I will investigate the associative participation in Oradea, on several levels: the participation rates by citizens, the type of associations in which oradeans participate and the profile of these NGOa€™s.
Hatos Roxana, Saveanu Tomina
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Correction: An Evaluation of Duplicate Adverse Event Reports Characteristics in the Food and Drug Administration Adverse Event Reporting System. [PDF]

Drug Saf
Janiczak S, Tanveer S, Tom K, Zhang R, Ma Y, Wolf L, Muñoz MA.   +6 more
europepmc   +1 more source

Restoring Administrations of Justice in Early Practice: American-Occupied Germany, 1945-1949

, 2014
Andrew Szanajda
openalex   +1 more source

EXOGENOUS CHALLENGES FOR THE TOURISM INDUSTRY IN THE BEGINNING OF THE TWENTY FIRST CENTURY [PDF]

Tourism is one of the fastest growing industries in the world. Besides its sustained growth the tourism industry has shown in the first years of the twenty first century that it can deal with political, military and natural disasters.
Akosz Ozan, Bac Dorin
core