Results 161 to 170 of about 9,194,937 (294)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
A new, patient-friendly, needleless methotrexate administration method using the pyro-drive jet injector in rats. [PDF]
Shimizu M, Shiga T, Hashiguchi M.
europepmc +1 more source
ETHICAL AND COMPETITIVE PROBLEMS RELATING TO QUOTA MILK SYSTEM IN ROMANIA [PDF]
Recent conflicts regarding the milk market indicat tensions between milk producers and milk processing companies, about milk price. This conflict involved many farmers and was focused in two directions.
Pop Cohut Ioana, Pup Anca
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Haemodynamic Changes After Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine Versus Placebo During Induction of General Anaesthesia: A Randomised Trial. [PDF]
Sjøen GH +4 more
europepmc +1 more source
CONSIDERATIONS ABOUT EVOLUTION, DENSITY AND SPECIALIZATION PERSPECTIVES OF SMES SECTOR IN THE WESTERN PART OF ROMANIA [PDF]
Starting from the role of small-and medium-sized enterprise (SME) sector that is widely recognized at European level in the generation of economic growth, regional development and work places, the present work of research aims to investigate the ...
Badulescu Alina, DODESCU Anca
core
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source

