Results 171 to 180 of about 9,451,716 (342)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

THE MANAGEMENT OF THE COMPANY THROUGH DIVIDEND AND THE ETHICAL DIMENSION OF THE DECISIONS TAKEN IN ETHIS FIELD [PDF]

The main objective of a company's shareholders is to increase its market value. Of course, they also wish, on a second level, to obtain dividends as big as possible from the investment they made.
Petru Prunea
core  

HOSPITAL ADMINISTRATION [PDF]

AJN, American Journal of Nursing, 1923
openaire   +1 more source

Protective effects by co-administration of eicosapentaenoic acid, capsaicin, and dextrin against obesity-related metabolic dysregulation in ob/ob mice

, 2018
Yoshihiko Hirotani, Rina Ueyama, Yoko Urashima, Ryuji Kato, Kenji Ikeda   +4 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Exploring innovative G-CSF schedules in AML cytarabine-based consolidation through a digital twin study of white blood cell recovery. [PDF]

PLoS One
Reimann AM, Schalk E, Mougiakakos D, Fischer T, Sager S.   +4 more
europepmc   +1 more source

EU AND GLOBALIZATION: SOME STYLIZED FACTS [PDF]

Most of the people all over the world claim that globalization is a result of dynamic interactions between economic, technological, social and political factors.
Castagna Alina, Furia Donatella, Scamuffa Domenico   +2 more
core  

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction

, 2021
Marta Tortajada, Cristina Prat‐Vidal, Miriam Font‐Morón, Marta Clos‐Sansalvador, Alexandra Calle, Paloma Gastelurrutia, Adriana Cserkóová, Anna Morancho, Miguel Ángel Ramírez, Anna Rosell, Antoni Bayés‐Genís, Carolina Gálvez‐Montón, Francesc E. Borràs, Santiago Roura   +13 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Analysis of Pharmacokinetic and Pharmacodynamic Interactions Between Chlorpromazine and Risperidone via Simultaneous Measurement of Multiple Receptor Occupancy in the Rat Brain. [PDF]

Biomedicines
Akashita G, Nakatani E, Tanaka S, Okura T.   +3 more
europepmc   +1 more source