Results 191 to 200 of about 3,501,089 (247)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A reanalysis of a genome-wide association study on breast cancer in Asian populations using the SG10K_Health reference panel for imputation: a multi-Centre case-control analysis. [PDF]

Hum Mol Genet
Chang X, Mariapun S, Li M, Wang L, Ho PJ, Khng AJ, Muir KR, Lophatananon A, Aronson KJ, Murphy RA, Kwong A, Au CH, Kim SW, Park SK, Stram DO, Wu AH, Teo SH, Yip CH, Tai NAM, MyBrCa Investigators, John EM, Kurian AW, Iwasaki M, Yamaji T, Choi JY, Kang D, Shu XO, Zheng W, Hartman M, Tan EY, Tan VK, Lim GH, Bolla MK, Dunning AM, Dennis J, Wang Q, Naven M, Easton DF, SG10K_Health Consortium, Dorajoo RS, Ho WK, Li J.   +41 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

The Effectiveness of Ketorolac in Relieving Pain Associated With Root Canal Therapy: A Systematic Review and Meta-Analysis. [PDF]

Clin Exp Dent Res
Ping R, Kang X, Fang R, Wang H, Wu LA.
europepmc   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Alternative Administration of Antiretroviral Therapy in People with HIV Unable to Swallow: A Scoping Review. [PDF]

HIV AIDS (Auckl)
Abdessamad H, Baroody C, Pogorzelski K, Jamaleddine W, Kitonga MS, Omar H, Amankrah SA, Allen-Brown K, Dandachi D.   +8 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Understanding real-world effectiveness of nirsevimab and the characteristics of breakthrough RSV infections: a study protocol of individual-participant-level data meta-analysis (the GEMINI study). [PDF]

BMJ Open Respir Res
Ren S, Zhang H, Deng S, Nair H, Li Y.
europepmc   +1 more source

Too much synchrony? Left bundle branch area pacing-induced systolic anterior motion and left ventricular outflow tract obstruction managed by intentional atrioventricular dyssynchrony. [PDF]

Korean J Intern Med
Jeong HK, Kim SS, Kim HK, Ki YJ, Choi DH, Park KH.   +5 more
europepmc   +1 more source

GABA-Producing Capabilities of <i>Lactococcus lactis</i> PL186 in Murine and Human. [PDF]

J Microbiol Biotechnol
Paek JJ, Yang H, Paek KS, Lee Y.
europepmc   +1 more source