Results 41 to 50 of about 13,521 (217)

An analytical model of inter-organizational relationships in project environment: A social network perspective

Tourism & Management Studies, 2014
To fulfill a project, there are varieties of organizations cooperating as a supply chain. Being in large numbers and diversity, the supply chain may result in complexity and uncertainty in managing the projects; although it provides the required ...
Samira Fallah, Naser Shams Gharneh
doaj  

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Evaluating Feral Swine Eradication and Control Pilot Program Impact on Crop Indemnities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT The 2018 Farm Bill established the Feral Swine Eradication and Control Pilot Program (FSCP), which was focused on removing feral hogs and restoring damaged property. We conduct a quasi‐experimental analysis of FSCP on crop damage using crop insurance data and a staggered difference‐in‐difference model.
Hence Duncan, Christopher N. Boyer, Eunchun Park, S. Aaron Smith   +3 more
wiley   +1 more source

Designing Cost‐Effective Carbon Payments to Induce Cellulosic Feedstock Production for Sustainable Aviation Fuel

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Perennial bioenergy crops, such as miscanthus and switchgrass, and crop residues have the potential to scale up sustainable aviation fuel (SAF) production and mitigate carbon emissions. However, high establishment costs, delayed returns, and risk–return profiles that diverge from those of conventional crops can hinder incentives to adopt ...
Fahd Majeed, Madhu Khanna, Ruiqing Miao
wiley   +1 more source

O planeamento da identidade da marca de destinos turísticos: aplicação do modelo de Aaker à marca Madeira

Tourism & Management Studies, 2013
Com o objetivo de aferir acerca da existência de uma visão partilhada relativamente à identidade e proposta de valor da marca Madeira, e considerando esta partilha essencial à existência de uma marca de sucesso, foi desenvolvido um estudo de carácter ...
Nélia Alves, Jorge Costa, Ana Salazar
doaj  

Sistemas de Información de Marketing: una visión integradora

Tourism & Management Studies, 2015
La información es un recurso imprescindible en la toma de decisiones de las organizaciones. Por ello, las organizaciones recurren a sistemas de información que les provean de este recurso básico. Un sistema de información es un medio por el que fluyen
Jesús Manuel López-Bonilla , Luis Miguel López-Bonilla, Jesús C. Peña-Vinces   +2 more
doaj   +1 more source

Dollars for Drops: Abatement Cost of Water for Irrigation in the Colorado River Basin

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT The Colorado River is a lifeline for more than 40 million people in the western United States. However, with climate change diminishing snowpacks in the Rocky Mountains and increasing demands from agriculture and urban areas, the river's flow has become insufficient to meet all the competing needs.
Shahin Bahrami, Mani Rouhi Rad, Rodolfo M. Nayga Jr.   +2 more
wiley   +1 more source

THE INTEGRAL RURAL TOURISM EXPERIENCE FROM THE TOURIST’S POINT OF VIEW – A QUALITATIVE ANALYSIS OF ITS NATURE AND MEANING

Tourism & Management Studies, 2011
Rural areas have attracted increasing interest as a space for leisure and tourism, as a result of recent trends in tourism demand, especially from urban populations.
ELISABETH KASTENHOLZ, JOANA LIMA
doaj