Results 11 to 20 of about 643,499 (354)
Comparing the Rates of Dopamine Hemodynamic Effect Onset after Infusion through Peripheral Veins in Three Regions [PDF]
Korean Journal of Critical Care Medicine, 2017 Background Dopamine is an inotropic agent that is often selected for continuous infusion. For hemodynamic stability, the rate of infusion is controlled in the range of 5-15 μg/kg/min. This study aimed to compare the time intervals from the administration
Deokkyu Kim +5 more
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Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response
Frontiers in Immunology, 2021 Vaccination is one of the most efficient public healthcare measures to fight infectious diseases. Nevertheless, the immune mechanisms induced in vivo by vaccination are still unclear.
Pierre Rosenbaum +29 more
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Pharmaceutics, 2023 mRNA-based vaccines have made a leap forward since the SARS-CoV-2 pandemic and are currently used to develop anti-infectious therapies. If the selection of a delivery system and an optimized mRNA sequence are two key factors to reach in vivo efficacy ...
Altan Yavuz +7 more
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Nanomedicine and versatile therapies for cancer treatment
MedComm, 2022 The higher prevalence of cancer is related to high rates of mortality and morbidity worldwide. By virtue of the properties of matter at the nanoscale, nanomedicine is proven to be a powerful tool to develop innovative drug carriers with greater ...
Aparna Shukla, Pralay Maiti
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Comparison of Genotype II African Swine Fever Virus Strain SY18 Challenge Models
Viruses, 2023 African swine fever (ASF) is a viral haemorrhagic disease found in domestic and wild boars caused by the African swine fever virus (ASFV). A highly virulent strain was used to evaluate the efficacy of newly developed vaccine candidates.
Xintao Zhou +10 more
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Importance of Nanoparticles for the Delivery of Antiparkinsonian Drugs
Pharmaceutics, 2021 Parkinson’s disease (PD) affects around ten million people worldwide and is considered the second most prevalent neurodegenerative disease after Alzheimer’s disease. In addition, there is a higher risk incidence in the elderly population.
Sara Silva +2 more
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Alternative Routes of Administration for Therapeutic Antibodies—State of the Art
Antibodies, 2022 Background: For the past two decades, there has been a huge expansion in the development of therapeutic antibodies, with 6 to 10 novel entities approved each year.
Aubin Pitiot +2 more
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Frontiers in Immunology, 2022 Innate immunity modulates adaptive immunity and defines the magnitude, quality, and longevity of antigen-specific T- and B- cell immune memory. Various vaccine and administration factors influence the immune response to vaccination, including the route ...
Yanis Feraoun +12 more
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Ocular Drug Delivery: Advancements and Innovations
Pharmaceutics, 2022 Ocular drug delivery has been significantly advanced for not only pharmaceutical compounds, such as steroids, nonsteroidal anti-inflammatory drugs, immune modulators, antibiotics, and so forth, but also for the rapidly progressed gene therapy products ...
Bo Tian +7 more
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Pharmaceuticals, 2020 Topotecan is actively used in clinic, with its primary use being in treatment of various types of cancer. The approved administration routes are oral and intravenous.
Seung-Hyun Jeong +2 more
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