Results 41 to 50 of about 643,499 (354)
Frontiers in Microbiology, 2020 Previous studies have identified oral administration of antibiotics and gut-impacting drugs as critical drivers for fecal antibiotic resistance (AR) and microbiome disruption in lab mice, but the practical implications of these findings have yet to be ...
Yang Zhou +14 more
doaj +1 more source
Plants, 2022 The use of cannabis and cannabinoid products for the treatment of neuropathic pain is a growing area of research. This type of pain has a high prevalence, limited response to available therapies and high social and economic costs.
Jose-Manuel Quintero +5 more
doaj +1 more source
Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]
, 2014 BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J +3 more
core +1 more source
Fuzzy based load and energy aware multipath routing for mobile ad hoc networks [PDF]
, 2015 Routing is a challenging task in Mobile Ad hoc Networks (MANET) due to their dynamic topology and lack of central administration. As a consequence of un-predictable topology changes of such networks, routing protocols employed need to accurately capture ...
Ali, M. +3 more
core +3 more sources
BMC Veterinary Research, 2021 Status epilepticus (SE) or prolonged epileptic seizure activity is a common neurological emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral damage and systemic complications.
Marios Charalambous +3 more
doaj +1 more source
Naloxone Administration Route in Opioid Overdose: A Review of Vermont EMS Data [PDF]
, 2017 Objective: Emergency Medical System (EMS) personnel administer the direct opioid antagonist naloxone in cases of opioid overdose via intramuscular (IM), intravenous (IV), subcutaneous (SQ), intraosseous (IO), or intranasal (IN) routes. Some early studies
LaMonda, Chris, MPH +4 more
core +1 more source
Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]
, 2016 Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana +3 more
core +2 more sources
Novel routes of opioid administration
British Journal of Anaesthesia, 1998 In the early days of anaesthesia, opioids were traditionally given by the intramuscular and intravenous routes and other methods of administration were considered as novel. However, because of expanding interest in both acute and chronic pain over the past few decades, the anaesthetist routinely administers opioids via the oral, subcutaneous, rectal ...
J M, Alexander-Williams, D J, Rowbotham
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source