Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
LA EXCEPCIONAL AUTOTUTELA EJECUTIVA DE LOS ACTOS ADMINISTRATIVOS EN CHILE
Revista de Derecho (Coquimbo)El presente artículo analiza la autotutela ejecutiva o ejecución de oficio de los actos administrativos, en otras palabras la facultad de la Administración del Estado consistente en aplicar la coacción, ante el desobedecimiento de sus actos por un ...
NICOLÁS ENTEICHE ROSALES
doaj +1 more source
Spread Trustee; Charitable Programme-related Investing; US exit taxes; Swiss Federal Administrative Court approach to foreign trusts and foundations; Singapore's approach to exchange of information; amendment to Sections 31 and 32 Trustee Act 1925; recovery of costs in probate litigation; thoughts on Sinclair v Versailles and constructive trusts generally [PDF]
, 2012 T. Molloy, T. Graham
openalex +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Regimul juridic al acţiunilor în contencios administrativ împotriva ordonanţelor Guvernului
Revista Transilvană de Ştiinţe Administrative, 2012 The present article presents a short analysis of the legal regime of the administrative contentious claims against the Government Ordinances, showing that the control of the courts of justice is limited, by report to the legal nature of the acts under ...
Camelia Florentina STOICA
doaj
Electricity Bill Act'2003 [PDF]
The Electricity Bill, 2003 passed by Parliament promises to usher in sweeping changes. The Bill seeks to provide a legal framework for enabling reforms and restructuring of the power sector.
Deepak Kumar, P Nair
core
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Ученые записки Казанского университета: Серия Гуманитарные науки, 2017 The paper deals with the legal aspects of notification problems of accomplished or planned official actions of courts, as well as administrative, civil, and legal enforcement systems and other institutions of power, administration, and control.
V.G. Sinitsyn
doaj
A Study on the Classification of Administrative Act - focusing on Permission, License and Approval -
, 2011 송시강
openalex +1 more source
, 2012 [Excerpt] In Shakespeare’s Henry IV, the lazy and lecherous Sir John Falstaff is attacked during battle, falls to the ground, and feigns his death. Falstaff attempts to justify his act of cowardice by explaining: “The better part of valor is discretion ...
Bertagna, Blake R.
core +1 more source