Results 141 to 150 of about 1,553,975 (340)

From AT&T to Brand X Declining Checks and Balances in an Increasingly Complex Marketplace [PDF]

open access: yes, 2006
When President Clinton signed the Telecommunications Act of 1996, he used the same pen that President Eisenhower used to sign legislation for the Interstate Highway system into law. It was a fitting analogy.
Hicks, Ross G.
core   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Adhuc Tacfarinas: the causes of the Tiberian war in North Africa (AD ca. 15-24) and the impact of the conflict on Roman imperial policy [PDF]

open access: yes, 2015
During the reign of Tiberius successive governors of Africa Proconsularis struggled to suppress a serious revolt by a number of semi-nomadic tribes led by Tacfarinas.
Vanacker, Wouter
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Market abuse [PDF]

open access: yes, 2002
On 1st December 2001, the Financial Services and Markets Act 2000 (‘FSMA’) came into force. One of its most controversial sections is Part VIII which gives the Financial Services Authority (‘FSA’) the power to impose civil penalties for market abuse ...
Alcock, A
core  

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Legal remedies in administrative court proceedings

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2010
Reform of the administrative judication process through a bill for the new Administrative Disputes Act in Croatian administrative court procedure introduces the right of appeal.
Inga Vezmar Barle
doaj  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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