Results 21 to 30 of about 116,396 (263)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Examining the complex and cumulative effects of environmental exposures on noise perception through interpretable spatio-temporal graph convolutional networks

Environment International
With the continuous expansion of urban populations, interactions between humans and their environments have grown increasingly frequent and complex. Traditional environmental studies often focus on isolated factors or specific locations, neglecting the ...
Liuyi Song, Mei-Po Kwan, Yang Liu
doaj   +1 more source

Reflections on “Centralization and the Civil Administrative Division” in the Nation-State Building Process during the Early Period of the Republic

Siyasal: Journal of Political Sciences, 2023
The founders of the Turkish Republic had in mind the idea and aim of building a modern nation-state and society. This idea and aim formed the basis of the approaches and policies adopted in the early period of the Republic.
Barış Kandeğer
doaj   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez, Jill O. Robinson, Wendy A. Allen‐Rhoades, Hadley S. Smith, Isabel Canfield, Rebecca L. Hsu, Sarah R. Scollon, Lauren R. Desrosiers‐Battu, Nicole M. Schneider, Frank Y. Lin, Donald Williams Parsons, Sharon E. Plon, Mary A. Majumder, Janet Malek, Amy L. McGuire   +14 more
wiley   +1 more source

Applying a “medical deserts” lens to cancer care services in the North-West region of Romania from 2009 to 2022 – a mixed-methods analysis

Archives of Public Health
Background Medical deserts pose significant challenges to healthcare systems worldwide, leading to unmet healthcare needs and exacerbated health issues, particularly in underserved regions.
Monica Georgiana Brînzac, Marius Ionuț Ungureanu, Cătălin Ovidiu Baba   +2 more
doaj   +1 more source

Exploring the factors behind the discrepancy between two-dimensional and three-dimensional indicators of greenspace exposure

Ecological Indicators
Assessing greenspace exposure is vital in environmental health research due to its impact on human health. Advances in technology, such as Light Detection and Ranging (LiDAR), enable precise three-dimensional (3D) greenspace assessments, measuring the ...
Lixian Su, Zihan Kan, Mei-Po Kwan
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

Impact of Venezuelan Migration on the Informal Workforce of Native Workers in Colombia

Economies
Colombia experienced a substantial increase in annual migration flow from Venezuela from 2013 to 2019, accumulating 1.7 million migrants by the end of 2019.
William Prieto Bustos, Cristian Darío Castillo Robayo, Jacobo Campo Robledo, Juliana Molina Dominguez   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Assessing physical and mental fatigue in construction workers: validating sweat lactate as a biomarker

Ain Shams Engineering Journal
This research tackles the challenge of accurately assessing fatigue among construction workers, a major factor in workplace accidents. Traditional methods often overlook the connection between physical and mental fatigue.
Jie Ma, Heng Li, Bo Fang, Zeyu Zhao, Imran Mehmood, Aamir Arsalan, Lei Wang   +6 more
doaj   +1 more source