Results 51 to 60 of about 116,396 (263)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Quantifying and enhancing the energy resilience of zero-emission train station systems against power outages via electrified train-building integrations

Energy Conversion and Management: X
Addressing power outages due to renewable energy penetration and conventional utility grid issues is vital to ensure the reliability and resilience of any energy system.
Gokula Manikandan Senthil Kumar, Sunliang Cao   +1 more
doaj   +1 more source

Incorporating 3D Building Data into National Spatial Data Infrastructure: Challenges and Insights from Slovenia [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Incorporating detailed 3D building data into national spatial data infrastructures (SDI) is associated with numerous technical and administrative challenges.
J. Tekavec, U. Drešček, E. Flogie Dolinar, A. Lisec   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peran Pemerintah Banyuwangi terhadap Bangunan Pinggir Pantai

Lentera Hukum, 2018
Banyuwangi is a regency in East Java which focuses to transforming the regency into a tourism city, especially in the coastal tourism. As the development has sustained, it persuades investors to explore coastal tourism as a new business area ...
Khairinisa Nur Firdausyah, Warah Atikah
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The administrative law aspects of physical planning in the Republic of Serbia: Building permit issuing procedure [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2018
One of the fundamental characteristics of the administrative law norms is its multiplicity. Alongside the General Part of the Administrative Law (legal norms applying to the administrative bodies including legal situations when all the administrative ...
Martinović Aleksandar L.
doaj  

Flexible Boron-Doped Diamond (BDD) Electrodes for Plant Monitoring

Sensors, 2017
Detecting the bio-potential changes of plants would be useful for monitoring their growth and health in the field. A sensitive plant monitoring system with flexible boron-doped diamond (BDD) electrodes prepared from BDD powder and resin (Nafion or Vylon ...
Shoko Tago, Tsuyoshi Ochiai, Seitaro Suzuki, Mio Hayashi, Takeshi Kondo, Akira Fujishima   +5 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Building a Local Administration Abroad [PDF]

Administory, 2017
Abstract Consulates, both in the 19th century and today, exist in a sort of hybrid space: Established by one sovereign entity in the territory of another, on the basis of exterritorial concessions, they depend on not one but two sets of legislation without being wholly defined by either one.
openaire   +1 more source