Results 161 to 170 of about 1,276,561 (325)
Administrative rules [replaced sheets]
, 1960 Includes [ORS] chapter 279, public contracts and purchasing [and] Attorney General's model rules and manual for public contracting.Title assigned by cataloger.This archived document is maintained by the State Library of Oregon as part of the Oregon ...
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Administrative Contract Extingshment and its Judicial Review [PDF]
, 2006 近年来，随着民主行政观念的深入及行政职权运作模式的转变，行政合同的运用日益受到行政主体的重视，行政合同纠纷也随之增多。但调整行政合同的实体及程序规范极其缺乏，理论及实务界对行政合同的性质、程序以及救济途径又观点不一。《行政程序法》试拟稿虽专章规定了行政合同，但合同消灭的性质、程序及审查未引起足够的重视。司法实践多参照适用《合同法》，却又与行政职权的运作存在冲突。特别是行政合同的消灭，影响相对方的权益，因此研究消灭程序规则及其审查十分必要。本文除引言外，共分为三章。第一章对合同解除与合同终止进行比较 ...
陈伏发
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Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation
Advanced Science, EarlyView.ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi +4 more
wiley +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Advanced Science, EarlyView.Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source
Fundamental change of circumstances in contract law
, 2010 Includes abstract.Includes bibliographical references (p. 246-263).Parties to a contract base their consensus on the facts known to them at the time of contracting - should there be an unforeseen change in these circumstances, it may no longer be just ...
Hutchison, Andrew
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Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source
Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China
Advanced Science, EarlyView.This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang +3 more
wiley +1 more source
Advanced Science, EarlyView.This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source