Results 191 to 200 of about 1,886,233 (353)

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Contract Administration, Part II: Managing Contract Changes

open access: yes, 2010
U.S. government agencies often struggle to clearly and concisely identify, communicate, and document their contract requirements to government contractors due to numerous factors, including; evolving technologies, urgent national security issues, re-prioritization of needs, changing funding profiles, acceleration and/or delay of the program schedule ...
Garrett, Gregory A., Rendon, Rene G.
openaire   +1 more source

Factors Driving Battery and Solar Purchase Decision of Residents: a Behavioural Choice Experiment Using a Hybrid Discrete Choice and Latent Variable Model

open access: yesAdvanced Sustainable Systems, EarlyView.
This article explores what drives households to adopt solar PV and battery systems in South East Queensland. Using hybrid discrete choice experiments, it reveals distinct adopter profiles and highlights cost, system size, and energy independence as key motivators.
Mohammad Alipour   +3 more
wiley   +1 more source

Molecular Simulation of Functionalized Covalent Organic Framework Membranes for Inorganic Salt Separation

open access: yesAdvanced Theory and Simulations, EarlyView.
Six functionalized TpPa‐based covalent organic frameworks (COFs) are characterized using nonequilibrium molecular dynamics simulations to assess water permeance and salt rejection. The TpPa‐SO3H COF membrane achieves the highest sodium sulfate rejection (>98%) while maintaining relatively high water permeance compared to commercial nanofiltration ...
Grace Wei   +3 more
wiley   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Assigning cancer stage to patients using administrative claims data: an example for colon and rectal cancers. [PDF]

open access: yesBMC Health Serv Res
Smith RA   +8 more
europepmc   +1 more source

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