Results 141 to 150 of about 29,912 (288)

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Visionary thought of professor Popović on administrative contracts

open access: yes, 2011
Rad je posvećen naučnim radovima profesora Slavoljuba Popovića o upravnim ugovorima. Autor predočava da je profesor Popović, temeljnim izučavanjem rešenja srodnih pravnih sistema i specifičnosti pojedinih država u njenim okvirima, kao i mogućnosti ...
Milovanović, Dobrosav
core  

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

open access: yesAdvanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun   +6 more
wiley   +1 more source

The Role of Family Ties in Agency Contracts. [PDF]

open access: yes
Drawing on data based on the entire population of Spanish newspapers over 27 years (1966-93), this study shows that firm performance and business risk are much stronger predictors of chief executive tenure when a firm's owners and its executive have ...
Núñez-Nickel, Manuel   +2 more
core  

Federal Enforcement Actions Against Medicare Advantage Plans. [PDF]

open access: yesJAMA Intern Med
Chen Z   +4 more
europepmc   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

The administrative of public contracts

open access: yes, 2018
Contrairement à la doctrine fiscale, la doctrine administrative de la commande publique, quand bien même son assise est ancienne, n’a constitué que récemment un objet d’étude.
Di Francesco, Dimitri
core  

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