Results 101 to 110 of about 22,706,981 (364)

The looked-after child in time: Creating and analysing longitudinal data on placement history and educational outcomes

open access: yesInternational Journal of Population Data Science, 2019
Background with rationale The Scottish government collects data on Looked-after-children (LAC) from the 32 local authorities (LAs) in Scotland. Since 2008, the LAs have provided individual data on a yearly basis that covers every child who was looked ...
Gillian Raab, Cecilia MacIntyre
doaj   +1 more source

The Good, the Bad, the Clunky: Improving the Use of Administrative Data for Research

open access: yesInternational Journal of Population Data Science, 2018
Introduction Administrative data arising via the operation of public service delivery systems hold great benefits for citizens and society by enabling new research questions to be addressed, providing they can be made available in a safe, socially ...
K. Jones   +4 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Better data, better knowledge, better society: Developing an ideal homelessness data system drawing on lessons from global practice

open access: yesInternational Journal of Population Data Science, 2019
The aim of this paper is to set out the principles of an ideal data system. Good data is crucial to effective policy and practice development in all social policy spheres and this is a particular challenge in the context of homelessness policy.
Ian Thomas, Peter Mackie
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Persisting social disadvantage and intercensal social mobility in Northern Ireland: an examination of morbidity and all-cause mortality using three waves of the Northern Ireland Longitudinal Study (NILS).

open access: yesInternational Journal of Population Data Science
Objective and Approach Using census returns from three waves of NILS (1991, 2001, 2011) linked with mortality data, we examined morbidity/mortality outcomes by socio-economic disadvantage over time (using an individual-level deprivation index derived ...
Rachel McCarter   +2 more
doaj   +1 more source

The association between mother’s alcohol consumption during pregnancy and their child’s educational attainment and risk of hospital admission by age 14

open access: yesInternational Journal of Population Data Science, 2019
Background Heavy alcohol consumption by mothers during pregnancy is associated with developmental problems in their children. However, the impact of light to moderate consumption on the long-term health and educational attainment up to adolescence has ...
Amrita Bandyopadhyay   +5 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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