Results 221 to 230 of about 24,701,264 (359)

Environmental drivers of CVD DALYs: 20-year macro-level evidence from China's administrative data. [PDF]

Int J Health Geogr
Li Y, Ran Q, Jiang H, Yao S.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Positive and unlabeled learning from hospital administrative data: a novel approach to identify sepsis cases. [PDF]

Health Care Manag Sci
Vogel J, Cordier J.
europepmc   +1 more source

Children with neurodevelopmental disorders and disabilities: a population‐based study of healthcare service utilization using administrative data

Developmental Medicine & Child Neurology, 2017
Rubab G. Arim, A. Miller, Anne Guèvremont, L. Lach, J. Brehaut, D. Kohen   +5 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Estimating the burden of dementia and parkinsonism through a novel identification algorithm based on healthcare administrative data. [PDF]

Front Public Health
Sabbatinelli J, Biscetti L, Lilla M, Giuliani A, Balducci F, Ramini D, Rupelli G, Pompili M, Pelliccioni G, Recchioni R, Capalbo M, Vanacore N, Olivieri F, Spazzafumo L.   +13 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Out-of-pocket expenditure for cataract surgery in rural China: a cross-sectional survey combined with hospital administrative data. [PDF]

Int J Equity Health
Zhao J, Hennessy J, Ma X.
europepmc   +1 more source