Results 181 to 190 of about 249,207 (257)

Optimising the prostate cancer diagnostic pathway in a tertiary hospital in Karachi: a two-cycle quality improvement project. [PDF]

BMJ Open Qual
Samad S, Samad H.
europepmc   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Letter to the Editor: Challenges of Using Administrative Data to Study Pediatric Tibial Tubercle Fracture-Associated Compartment Syndrome. [PDF]

HSS J
Bašković M, Pešorda D.
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

From legacy systems to real-time response: VPD-SMART implementation and its impact on public health surveillance in Paraguay and the Americas.

SSM Health Syst
Ortiz C, Millacura FA, Atavillos C, Bravo-Alcántara P, Espinoza J, Osorio V, Baeza C, Ojeda P, Revilla F, Pacis C, Bobadilla S, Araceli F, Del Medico P, Tejo C, Rossi E, Ordoñez F, Zapata-Bedoya S, Cain E, Tavera P, Magarinos M, Whittembury A, Jean-Baptiste A, Broome K, Ovelar P, Perez T, García M, Villalobos N, Potter R, Cousirat L, Rey-Benito G, Velandia-Gonzalez M.   +30 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Implementation of AESOP early-warning system for respiratory disease: a pilot and validation study using routinely collected data in Amazonas, Brazil. [PDF]

Lancet Reg Health Am
Marcilio I, Ramos PIP, Florentino PVT, Dos Santos ASM, de Araújo Oliveira V, Carreiro RP, Lima Danielli RC, Zany Dos Reis A, Ramos TCA, Bartholomay P, Coradi de Freitas DR, Martins Romano AP, Nunes Dos Santos C, Nienov OH, Gaete RAC, Oliveira JF, Cunha GG, Cunha MCSL, Brandão de Miranda R, Boaventura VS, Andrade RFS, Landau L, Penna GO, Barral-Netto M, ÆSOP Collaborating Team.   +24 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source