Results 31 to 40 of about 20,367 (257)

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

ADMINISTRATIVE DISCRETION IN ADMINISTRATIVE-DELICT LAW [PDF]

Naukovyy Visnyk Dnipropetrovs kogo Derzhavnogo Universytety Vnutrishnikh Sprav
The article deals with the theoretical concept of "discretion" in the law. The doctrinal approaches to the understanding of "discretion", "administrative discretion", as well as generalizations of judicial practice, allowing to find out the content of discretion, are analyzed.
openaire   +1 more source

"The Electronic administrative decision and discretion authority of public administration"

International Journal of Electronic Security and Digital Forensics, 2023
This study deals with the electronic administrative decision and discretionary authority of public administration, it is known that the developments of life obliged the public administration to use technology in its administrative transactions, so the use of technological means enables the administration to issue its administrative decisions by using ...
openaire   +1 more source

Factors Associated with Fibromyalgia Diagnosis amongst People Meeting Criteria: Results from UK Biobank

Arthritis Care &Research, Accepted Article.
Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification. This study
Sung‐A Kim, Gary J. Macfarlane, Marcus J. Beasley   +2 more
wiley   +1 more source

Administrative Discretion in the Investigation of Industrial Accidents and Administrative Investigations in Cases of Violations of State Regulatory Requirements for Occupational Health and Safety

Сибирское юридическое обозрение
The participation of the public administration in the investigation of accidents is interconnected with the proceedings on administrative offenses regarding state regulatory requirements for occupational health and safety.
A. V. Terekhova
doaj   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Concept, Indications and Classification of Administrative Discretion

Vestnik Omskoj Ûridičeskoj Akademii, 2014
Nowadays discretion is the notion used loosely enough in the legal sphere. Consequently, in different situations connected with application of discretion it is interpreted in different ways.
Girvits A. V.
doaj  

Grounds for Judicial Intervention in Administrative Discretion in Considering Cases of Administrative Offenses

Сибирское юридическое обозрение
Drawing from judicial practice, the article addresses the theoretical question of the procedural situations under the Code of Administrative Offenses in which courts intervene in the discretion of administrative authorities.
S. V. Schepalov
doaj   +1 more source