Results 111 to 120 of about 361,790 (304)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Fundamental Determinants of Administrative Court Dispute

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2014
Administrative Court proceedings are more or less subject to the same limits in various countries even though certain differences related to the accepted model exist.
Daniel Giltard
doaj  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Reflexive transnational law : the privatisation of civil law and the civilisation of private law [PDF]

open access: yes, 2005
The author examines the emergence of a transnational private law in alternative dispute resolution bodies and private norm formulating agencies from a reflexive law perspective. After introducing the concept of reflexive law he applies the idea of law as
Calliess, Gralf-Peter
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

NEW FACTS AND NEW EVIDENCE AS THE BASIS FOR REOPENING AN ADMINISTRATIVE DISPUTE IN THE REPUBLIC OF SRPSKA

open access: yesГодишњак Правног факултета у Бањалуци
According to the Law on Administrative Dispute of Republic of Srpska, new facts and new evidence present a legal basis that provides the possibility for the dissatisfied parties to request a reopening of an administrative dispute even after alegally ...
Дражен Миљић
doaj   +1 more source

Strategies for Resolving Administrative Disputes

open access: yesJournal of Legal and Political Studies
Administrative disputes are among the most important issues that significantly impact the effectiveness of government performance and the stability of relations between the administration and individuals. Traditional methods of resolving these disputes, such as direct recourse to the courts, often result in prolonging the conflict and wasting time ...
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Stability maintenance at the grassroots: China’s weiwen apparatus as a form of conflict resolution [PDF]

open access: yes, 2013
This working paper explores the history and potential of “stability maintenance” (weiwen) as a form of conflict resolution in China. Its emphasis on conflict resolution is novel.
Benney, Jonathan
core  

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