Results 81 to 90 of about 788,725 (322)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Uniform Interpretation and Application of Law and the Uniqueness of Court Practice in Administrative Adjudication Process

Zbornik Radova Pravnog Fakulteta u Splitu, 2012
The aim of this paper is to analyse what effect on the uniform interpretation and application of administrative law in Croatia, its consequence and the uniqueness of administrative legal practice will have on the new Administration Dispute Act.
Damir Aviani, Dario Đerđa
doaj  

Historical development of administrative dispute in legal science [PDF]

Baština, 2018
Based on the application of historical method, content analysis, historical analysis and another scientific methods of social and legal sciences, it is undisputable that administrative dispute and control of administrative acts by the courts appears at ...
Jakšić Milena V., Macura Milan M.
doaj  

O potrzebie alternatyw dla sądowego rozstrzygania sporów pomiędzy władzami administracyjnymi a podmiotami prywatnymi w świetle Zalecenia Komitetu Rady Ministrów R (2001)9

Studia Prawa Publicznego, 2018
The aim of the article is to explain the reasons for the introduction of mediation in administrative law. Mediation is presented in the light of the Recommendation of the Committee of the Council of Ministers R (2001)9 of 5 September 2001 on ...
Bartłomiej Chludziński
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Obligation and implementation of decisions in administrative dispute resolution

Zbornik Radova Pravnog Fakulteta u Splitu, 2012
In this paper the problem area of obligation and implementation of decisions reached in administrative dispute resolution is analysed. In the introductory part of the paper the importance of the concept of obligation of court decisions for an effective ...
Marko Šikić
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The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

MEDIATION AS AN ALTERNATIVE WAY TO RESOLVE ADMINISTRATIVE DISPUTES

, 2021
S. O. KORINNYY
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

REKONSTRUKSI PENYELESAIAN SENGKETA ADMINISTRASI DAN HASIL PEMILIHAN GUBERNUR, BUPATI DAN WALIKOTA

Arena Hukum, 2016
  Administrative dispute resolution, as well as results in elections for governor, regent and mayor today, may raise many legal issues. Some of such issues are the State Administrative Court’s inexecutable decision’s, the decision’s contradicting
Much. Anam Rifa'i
doaj   +1 more source