Results 51 to 60 of about 2,659 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cases of Administrative Court Taxation Law Dispute Resolution and their contribution to legal security [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2015
This paper points out the advances made in dispute resolution in the area of taxation Law from the enactment of the Administrative Law Act of 2012. Similarly, the difficulties in the application of Finance Law are pointed out both in the actions of both ...
Hrvoje Jelić, Kornelija Miše Bobinac
doaj   +2 more sources

PERLINDUNGAN HUKUM UNDANG-UNDANG NOMOR 30 TAHUN 2014 BAGI PEGAWAI NEGERI SIPIL YANG DIBERHENTIKAN DAN IMPLIKASINYA TERHADAP KEWENANGAN BADAN PERTIMBANGAN KEPEGAWAIAN

open access: yesJurnal Idea Hukum, 2018
Legal protection of civil servants (PNS) in a dispute over staffing has undergone a paradigm shift with the enactment of Law No. 30 of 2014 on Government Administration (UUAP).
Arief Rachman Hakim
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Administrative Appeal Efforts in Indonesian Administrative Dispute Resolution After the Government Administration Law (Pre-Omnibus Law)

open access: yesAhmad Dahlan Legal Perspective, 2022
Administrative effort is an effort to resolve disputes in the Indonesian State Administrative Court. This administrative effort changed after the Omnibus Law was introduced. However, the Omnibus Law itself will be changed in the future because there is a demand for a constitutional court decision. Therefore, administrative efforts have the potential to
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

APPLICATION OF LEGAL FICTION IN THE INSTITUTION OF CITIZEN PROTECTION FROM ADMINISTRATIVE SILENCE

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2008
In this paper, fi ction as a basic legal technique in the regulation of legal protection of citizens from administrative silence in the Republic of Croatia is analysed.
Marko Šikić
doaj  

Review of Dispute Resolution of Heritage Assets and Administration of A Will in Evidence of Disputes [PDF]

open access: yesSultan Agung Notary Law Review, 2020
The purpose of this study is to determine and analyze: 1) Legal construction for the making of wills in the planning of distribution of inheritance. 2) The roles and responsibilities of a notary in the execution of a will. 3). The position of the will in proving inheritance disputes at the Kendari Religious Court based on Decision No.384.Pid.B/2018/PN ...
openaire   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

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