Results 131 to 140 of about 27,411 (263)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Legal and ethical conflicts in hospital settings: thematic synthesis of qualitative studies focused on nursing practice. [PDF]

BMC Med Ethics
Yarahmadi S, Cheraghian T, Jafarifar S.
europepmc   +1 more source

Engineering Free Volume within Frontal Ring‐Opening Metathesis Polymerization via Pendant Plasticization

Advanced Materials, EarlyView.
Norbornene‐based copolymers with tunable n‐alkyl pendant length provide control over matrix free volume, enabling elastomeric materials via frontal ring‐opening metathesis polymerization (FROMP). ABSTRACT Frontal ring‐opening metathesis polymerization (FROMP) enables rapid, energy‐efficient access to high‐performance thermosets and thermoplastics, but ...
Kevin A. Stewart, Francesca J. Lombardi, Sky D. Cao, Claire M. Massouh, Jacob J. Lessard   +4 more
wiley   +1 more source

Clinical phenotypes of psychosis and reoffending risk among justice-involved adolescents: a population-based cohort study. [PDF]

Front Psychiatry
Akpanekpo EI, Butler T.
europepmc   +1 more source

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source

Public health, research, and procedural justice. [PDF]

Osong Public Health Res Perspect
Lee JK.
europepmc   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

What goals does China's medical insurance fund supervision aim to achieve? A quantitative analysis based on national-level policies. [PDF]

BMC Health Serv Res
Xu J, Cheng F, Jiang X, Zuo X, Yin W, Cui L, Wang D, Kang Z.   +7 more
europepmc   +1 more source

Tunable Plasmonic Response of Silver Nanoparticles Entangled in Detonation Nanodiamond Network via Colloidal Self‐Assembly

Advanced Materials Interfaces, EarlyView.
Detonation nanodiamonds form a network that entangles silver nanoparticles into stable nanocomplexes. The structure can fine‐tune and enhance plasmonic absorption through nearfield electromagnetic interactions but prevents silver particle aggregation. The study shows how the arrangement and concentration of particles affect light absorption, offering a
Vendula Hrnčířová, Markéta Šlapal Bařinková, Muhammad Qamar, Kateřina Kolářová, Bohuslav Rezek   +4 more
wiley   +1 more source