Results 61 to 70 of about 884,853 (293)

POLICY options [PDF]

open access: yes, 2009
End of project reportThe incomes of Irish cattle farmers benefited greatly from the reform of the CAP for beef and cereals in 1992 and more recently under Agenda 2000.
Dunne, William   +2 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The role of the bid examination committee in administrative contracting in KSA and UAE: a systematic review

open access: yesCogent Social Sciences
The objective of this systematic review was to know the role of the bid examination committee in administrative contracting in Saudi Arabia and United Arab Emirates. Following the PRISMA protocol, we conducted a review of papers published in 3 databases (
Dawood Abdulaziz Al-Dawoud
doaj   +1 more source

Decommissioning of the ASTRA research reactor: Planning, executing and summarizing the project [PDF]

open access: yesNuclear Technology and Radiation Protection, 2010
The decommissioning of the ASTRA research reactor at the Austrian Research Centres Seibersdorf was described within three technical papers already released in Nuclear Technology & Radiation Protection throughout the years 2003, 2006, and 2008 ...
Meyer Franz
doaj   +1 more source

Proceedings of the Fifth World Conference on Earthquake Engineering [Book Review] [PDF]

open access: yes, 1975
The recently issued two-volume set of the Proceedings of the Fifth World Conference on Earthquake Engineering consists, essentially, of all the papers presented at the last world conference held in Rome in July of 1973.
Jennings, Paul C.
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

How to close the productivity gap between the US and Europe: A quantitative assessment using a semi-endogenous growth model [PDF]

open access: yes
This paper uses a semi-endogenous growth model to identify possible sources for three interrelated stylised differences between the EU and the US, namely a higher level of productivity and knowledge investment and larger skill premia in the US compared ...
Jan in 't Veld   +2 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Report on the evaluation of the pilot case studies (= Deliverable D4 of the Project European Information System for Organic Markets, QLK5-2002-02400), including Annex 1: National working papers on pilot applications (DCPS) in eight European countries and Annex 2 Guidelines on evaluating pilot applications (DCPS) in eight European Countries [PDF]

open access: yes, 2005
The current situation of market information systems on organic farming in Europe shows a substantial lack of information. Although previous EU-research projects such as OFCAP (FAIR3-CT96-1794) and OMIaRD (QLK5-2000-01124) have shown that regional or ...
Gleirscher, Norbert   +3 more
core  

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