Results 251 to 260 of about 1,890,729 (361)

Variation in Neurodegeneration‐Linked Brain Regions in Young Adult APOE E4 Carriers With Spina Bifida

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Possible pleiotropic effects of apolipoprotein E4 (APOE E4) in individuals with congenital brain malformations are relatively unknown. Our goal was to determine if neurodegeneration‐linked brain region volumes differ significantly between E4 carriers and noncarriers in young adults with spina bifida (SB). Methods Eleven individuals ( 
Joan M. Jasien   +8 more
wiley   +1 more source

ADMIRALTY ADMINISTRATION AND PERSONNEL, 1619–1714

open access: yesHistorical Research, 1936
G. F. James, J. J. Sutherland Shaw
openaire   +2 more sources

Effect of Mild to Moderate Hepatic Impairment on Valemetostat Pharmacokinetics: An Open‐Label, Phase I Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana   +8 more
wiley   +1 more source

Explaining the barriers and facilitators of the accreditation process in maternity departments. [PDF]

open access: yesBMC Nurs
Hezbiyan Z   +10 more
europepmc   +1 more source

A Randomized Thorough QT Trial Using Concentration‐QT Analysis to Evaluate the Effects of Centanafadine on Cardiac Repolarization

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Centanafadine is a norepinephrine/dopamine/serotonin reuptake inhibitor in development for treatment of attention‐deficit/hyperactivity disorder. This double‐blind, placebo‐ and moxifloxacin‐controlled, 3‐period crossover trial evaluated the effects of centanafadine (EB‐1020) and its metabolite (EB‐10601) on cardiac repolarization in 30 ...
Osman S. Turkoglu   +3 more
wiley   +1 more source

Increasing hospital administrative efficiency via optimized office automation systems: A PDCA cycle approach. [PDF]

open access: yesPLoS One
Lu R   +11 more
europepmc   +1 more source

Pharmacokinetics, Bioequivalence, and Safety Studies of Crisaborole Ointment in Healthy Chinese Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract The aim of this study was to evaluate the bioequivalence and safety of a single application of crisaborole ointment to test formulation and reference formulation in healthy subjects under fasting conditions. A total of 32 subjects were included and divided into 2 groups (test‐reference; reference‐test).
Yanchao Wang   +9 more
wiley   +1 more source

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