Results 131 to 140 of about 1,121,426 (340)

Procedural rights in composite administrative procedures

open access: yes, 2020
The two contributions in this legal working paper discuss the various aspects of composite administrative procedures in the context of both Single Supervisory Mechanism (SSM) and Single Resolution Mechanism (SRM) decision-making procedures. It addresses the definition of such procedures, their relevance in the SSM and SRM context, the allocation of ...
Eckes, C., D’Ambrosio, R.
openaire   +2 more sources

From the Idea to the Realization of the Wind Farm - Overview of the Administrative Procedure and Legal Regulations in the Republic of Serbia [PDF]

open access: diamond
Miloš Ječmenica   +3 more
openalex   +1 more source

Executive power bodies as the subjects of Administrative procedure law [PDF]

open access: yes, 2015
Джафарова, М. В. Органи виконавчої влади як суб`єкти адміністративно-процесуального права / М. В. Джафарова // Науковий вісник Ужгородського національного університету : серія: Право. – Ужгород : Видавничий дім «Гельветика», 2015. – Вип. 33. Т. 2.
Dzhafarova, M. V.   +2 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Administrative protection of participants in the procedure of public procurement under Croatian law

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2011
Public procurement in Croatia was legislatively regulated for the first time in 1997. The system for administrative protection of the participant rights in public procurement was only established in 2001.
Dragan Medvedović
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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